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闭合复位治疗发育性髋关节发育不良后骨骺骨坏死的斯皮卡磁共振成像预测因素

Spica MRI predictors for epiphyseal osteonecrosis after closed reduction treatment of dysplasia of the hip.

作者信息

Haruno Lee S, Kan J Herman, Rivlin Michael J, Rosenfeld Scott B, Schallert Erica K, Zhu Huirong, Shenava Vinitha R

机构信息

Department of Orthopedic Surgery, Cedars-Sinai Medical Center, Los Angeles, California.

Baylor College of Medicine.

出版信息

J Pediatr Orthop B. 2019 Sep;28(5):424-429. doi: 10.1097/BPB.0000000000000606.

Abstract

Spica MRI with intravenous gadolinium contrast after closed reduction for developmental dysplasia of the hip (DDH) helps to determine successful reduction and attempts to identify patients at risk for epiphyseal osteonecrosis. The objective of our study was to evaluate spica MRI predictors for epiphyseal osteonecrosis after closed reduction. This was a retrospective study of all patients undergoing closed reduction for DDH followed by gadolinium-enhanced spica MRI between July 2011 and November 2014. Patient demographics and clinical follow-up through 2017, including the development of epiphyseal osteonecrosis and need for reintervention after the initial reduction, were recorded. MRI data included hip abduction angles and quantifying the percentage of femoral head enhancement. Twenty-five hips in 21 patients (16 girls, five boys, mean age: 0.99 years, range: 0.4-3.1 years) were included in our study. The mean follow-up period was 3 ± 1.5 years (range: 0.65-6.1 years). Eight (32%) of 25 hips went on to develop osteonecrosis. Epiphyseal osteonecrosis was more likely with less than 80% enhancement (sensitivity 87.5%, specificity 88.25%, positive predictive value 78%, negative predictive value 94%). The mean contrast enhancement for patients developing osteonecrosis compared with those who did not was 37.5 and 86.5%, respectively; P = 0.001. Immediate postspica MRI with gadolinium is a useful prognostic tool for determining future risk for epiphyseal osteonecrosis in children treated for DDH. Our data complement existing literature and suggest that even in cases with partial epiphyseal enhancement, osteonecrosis may still develop. When the epiphyseal enhancement is less than 80%, it is recommended that spica cast revision is considered.

摘要

对于发育性髋关节发育不良(DDH),在闭合复位后进行静脉注射钆对比剂的髋人字石膏MRI有助于确定复位是否成功,并试图识别有骨骺坏死风险的患者。我们研究的目的是评估闭合复位后骨骺坏死的髋人字石膏MRI预测指标。这是一项对2011年7月至2014年11月期间所有接受DDH闭合复位并随后进行钆增强髋人字石膏MRI检查的患者的回顾性研究。记录了患者的人口统计学数据以及截至2017年的临床随访情况,包括骨骺坏死的发生情况以及初次复位后是否需要再次干预。MRI数据包括髋关节外展角度以及股骨头强化百分比的量化。我们的研究纳入了21例患者的25个髋关节(16名女孩,5名男孩,平均年龄:0.99岁,范围:0.4 - 3.1岁)。平均随访期为3 ± 1.5年(范围:0.65 - 6.1年)。25个髋关节中有8个(32%)发生了坏死。强化低于80%时更易发生骨骺坏死(敏感性87.5%,特异性88.25%,阳性预测值78%,阴性预测值94%)。发生坏死的患者与未发生坏死的患者相比,平均对比剂强化分别为37.5%和86.5%;P = 0.001。钆增强的髋人字石膏MRI检查后即刻成像对于确定接受DDH治疗的儿童未来发生骨骺坏死的风险是一种有用的预后工具。我们的数据补充了现有文献,并表明即使在骨骺部分强化的情况下,仍可能发生坏死。当骨骺强化低于80%时,建议考虑更换髋人字石膏。

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