经内镜抽吸治疗急性肠系膜上动脉栓塞
Aspiration therapy for acute embolic occlusion of the superior mesenteric artery.
机构信息
Department of Vascular Surgery, Xuanwu Hospital, Capital Medical University, Beijing 100053, China.
Center of Evidence-Based Medicine, Xuanwu Hospital, Capital Medical University, Beijing 100053, China.
出版信息
World J Gastroenterol. 2019 Feb 21;25(7):848-858. doi: 10.3748/wjg.v25.i7.848.
BACKGROUND
Embolic superior mesenteric artery (SMA) occlusion is associated with high mortality rates. Delayed treatment often leads to serious consequences, including intestinal necrosis, resection, and even patient death. Endovascular repair is being introduced, which can improve clinical symptoms and prognosis and decrease the incidence of exploratory laparotomy. Many reports have described successful endovascular revascularization of embolic SMA occlusion. However, most of those reports are case reports, and there are few reports on Chinese patients. In this paper, we describe the technical and clinical outcomes of aspiration therapy using a guiding catheter and long sheath technique which facilitates the endovascular repair procedure.
AIM
To evaluate the complications, feasibility, effectiveness, and safety of endovascular treatment for the acute embolic occlusion of the SMA.
METHODS
This retrospective study reviewed eight patients (six males and two females) from August 2013 to October 2018 at Xuanwu Hospital, Capital Medical University. The patients presented with acute embolic occlusion of the SMA on admission and were initially diagnosed by computed tomography angiography (CTA). The patients who underwent endovascular treatment with a guiding catheter had no obvious evidence of bowel infarct. No intestinal necrosis was identified by gastrointestinal surgeons through peritoneal puncture or CTA. The complications, feasibility, effectiveness, safety, and mortality were assessed.
RESULTS
Six (75%) patients were male, and the mean patient age was 70.00 ± 8.43 years (range, 60-84 years). The acute embolic occlusion of the SMA was initially diagnosed by CTA. All patients had undertaken anticoagulation primarily, and percutaneous aspiration using a guiding catheter was then undertaken because the emboli had large amounts of thrombus residue. No death occurred among the patients. Complete patency of the suffering artery trunk was achieved in six patients, and defect filling was accomplished in two patients. The in-hospital mortality was 0%. The overall 12-mo survival rate was 100%. All patients survived, and two of the eight patients had complications (the clot broke off during aspiration).
CONCLUSION
Aspiration therapy is feasible, safe, and beneficial for acute embolic SMA occlusion. Aspiration therapy has many benefits for reducing patients' death, resolving thrombi, and improving symptoms.
背景
栓塞性肠系膜上动脉(SMA)闭塞与高死亡率相关。延迟治疗通常会导致严重后果,包括肠坏死、切除,甚至患者死亡。血管内修复正在引入,可以改善临床症状和预后,并降低剖腹探查的发生率。许多报道描述了成功的栓塞性 SMA 闭塞的血管内再血管化。然而,大多数这些报道是病例报告,并且关于中国患者的报告很少。在本文中,我们描述了使用引导导管和长鞘技术进行抽吸治疗的技术和临床结果,该技术有利于血管内修复过程。
目的
评估血管内治疗急性栓塞性 SMA 闭塞的并发症、可行性、有效性和安全性。
方法
这项回顾性研究回顾了 2013 年 8 月至 2018 年 10 月期间首都医科大学宣武医院的 8 名患者(6 名男性和 2 名女性)。这些患者入院时被诊断为急性栓塞性 SMA 闭塞,并通过计算机断层血管造影术(CTA)初步诊断。接受引导导管血管内治疗的患者没有明显的肠梗死证据。胃肠外科医生通过腹腔穿刺或 CTA 未发现肠坏死。评估并发症、可行性、有效性、安全性和死亡率。
结果
6 名(75%)患者为男性,平均患者年龄为 70.00±8.43 岁(范围,60-84 岁)。急性栓塞性 SMA 闭塞最初通过 CTA 诊断。所有患者均接受抗凝治疗,由于栓塞物含有大量血栓残留物,因此随后进行了经皮抽吸引导导管治疗。患者均未死亡。6 名患者的受累动脉主干完全通畅,2 名患者的缺损得到填充。住院期间死亡率为 0%。总的 12 个月生存率为 100%。所有患者均存活,8 名患者中有 2 名出现并发症(抽吸时血栓破裂)。
结论
抽吸治疗对于急性栓塞性 SMA 闭塞是可行、安全和有益的。抽吸治疗对于降低患者死亡率、解决血栓和改善症状有很多好处。