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[采用米氏法可控膀胱造瘘术的长期随访:5年后]

[Long-term follow-up of continent cystostomy with the Mitrofanoff procedure: 5 years later].

作者信息

Poncet D, Boillot B, Thuillier C, Descotes J-L, Rambeaud J-J, Lanchon C, Long J-A, Fiard G

机构信息

Service d'urologie, CHU de Grenoble, BP 217, 38043 Grenoble cedex 9, France.

Service d'urologie, CHU de Grenoble, BP 217, 38043 Grenoble cedex 9, France.

出版信息

Prog Urol. 2019 Mar;29(3):147-155. doi: 10.1016/j.purol.2018.12.006. Epub 2019 Feb 26.

Abstract

INTRODUCTION

This study analyzed long-term functional outcome of continent catheterizable channels with the Mitrofanoff procedure, their continence, complications and the satisfaction of the patients.

MATERIAL AND METHOD

Data from patients who underwent a Mitrofanoff procedure at our institution from June 1997 to March 2015 were retrospectively collected. All patients were contacted at the end of the study, a survey was submitted to them.

RESULTS

Sixty-seven patients underwent a continent cystostomy with the Mirtrofanoff procedure. Forty-five patients had the inclusion criteria: 18 years old or older, no previous urinary diversion with a minimum of 6 months of follow-up. The cohort comprised mainly neurologic bladder (84 %) with spinal cord injuries (54 %) or spina-bifida patients (15 %). Median age was 35 years old [22-49]. Median follow-up was 64months [39-90]. The surgical procedure used an appendicular channel: 30 patients (67 %) or a continent ileal plasty: 15 patients (33 %). At the end of follow-up: 88 % patients have a full cystostomy continence, 89 % full uretral continence. Twenty-nine patients had one (41 %) or more reinterventions. Reasons for the 58 reinterventions were: stomal stenosis (31 %), uretral incontinence (29 %), cystostomy incontinence (15 %), lithiasis (9 %). Those reinterventions were done with a local surgery (31 %) or an endoscopic surgery (35 %). Overall early adverse events (<30days) or delayed (>30days) adverse events were similar (P=0.93) in appendicovesicostomy group or continent ileal plasty group. Ninety-four percent patients described a satisfactory urinary comfort. The cystostomy was considered esthetic by 71 %, its realization allowed an improvement of the quality of life for 89 % of them.

CONCLUSION

Continent channels in adults demonstrate favorable long-term outcomes even if reinterventions could be necessary to maintain a continent and catheterizable channel. Despite reinterventions, patients remain satisfied by the Mitrofanoff procedure which facilitate the process of clean intermittent catheterization.

LEVEL OF EVIDENCE

摘要

引言

本研究分析了采用米氏术式构建的可控性膀胱造瘘通道的长期功能结果、控尿情况、并发症以及患者满意度。

材料与方法

回顾性收集了1997年6月至2015年3月在我院接受米氏术式的患者数据。在研究结束时联系了所有患者,并向他们发放了调查问卷。

结果

67例患者接受了米氏术式的可控性膀胱造瘘术。45例患者符合纳入标准:年龄18岁及以上,既往无尿流改道术史,且随访至少6个月。该队列主要包括神经源性膀胱患者(84%),其中脊髓损伤患者(54%)和脊柱裂患者(15%)。中位年龄为35岁[22 - 49岁]。中位随访时间为64个月[39 - 90个月]。手术采用阑尾通道:30例患者(67%),或可控性回肠成形术:15例患者(33%)。随访结束时:88%的患者膀胱造瘘完全可控,89%的患者尿道完全可控。29例患者进行了一次(41%)或更多次再次干预。58次再次干预的原因包括:造口狭窄(31%)、尿道失禁(29%)、膀胱造瘘失禁(15%)、结石(9%)。这些再次干预采用局部手术(31%)或内镜手术(35%)进行。阑尾膀胱造瘘组或可控性回肠成形术组的总体早期不良事件(<30天)或延迟不良事件(>30天)相似(P = 0.93)。94%的患者表示排尿舒适度令人满意。71%的患者认为膀胱造瘘美观,其实施使89%的患者生活质量得到改善。

结论

成人可控性通道显示出良好的长期结果,即使可能需要再次干预以维持可控且可导尿的通道。尽管有再次干预,但患者对米氏术式仍感到满意,该术式便于清洁间歇性导尿过程。

证据水平

4级。

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