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双侧外侧膝状体病变导致一名患有后部可逆性脑病综合征的患者出现可逆性失明。

Bilateral lateral geniculate body lesions causing reversible blindness in a patient with posterior reversible encephalopathy syndrome.

作者信息

Karadan Ummer, Supreeth R N, Chellenton Jayakrishnan, Ummer Abin, Muthyala Prathap Reddy

机构信息

Department of Neurology, Baby Memorial Hospital, Kerala, India.

C-Block, Baby Memorial Hospital, Arayudathupalam, Calicut, Kerala 673001, India,

出版信息

J R Coll Physicians Edinb. 2019 Mar;49(1):34-36. doi: 10.4997/JRCPE.2019.107.

Abstract

Posterior reversible encephalopathy syndrome (PRES) is a completely reversible neuroradiological entity caused by accelerated hypertension, eclampsia, certain cytotoxic drugs and acute renal failure. PRES involves posterior circulation of the brain resulting in various manifestations, hence the name. Acute vision loss is one of the manifestations that occurs owing to the involvement of the visual pathway. However, loss of vision due to a lesion involving the lateral geniculate body alone is unusual. We report one such case of a young female who developed acute bilateral painless loss of vision without any other symptom during postpartum period. MRI brain showed features of PRES involving bilateral lateral geniculate body, hippocampus and brainstem. There was no involvement of retrogeniculate visual pathway, i.e. parieto-occipital cortex. The patient improved with optimal blood pressure control and was discharged after 5 days.

摘要

后部可逆性脑病综合征(PRES)是一种由高血压急症、子痫、某些细胞毒性药物和急性肾衰竭引起的完全可逆的神经放射学病症。PRES累及脑的后循环,导致各种表现,因此得名。急性视力丧失是由于视觉通路受累而出现的表现之一。然而,仅因外侧膝状体病变导致的视力丧失并不常见。我们报告了这样一例年轻女性病例,她在产后出现急性双侧无痛性视力丧失,无任何其他症状。脑部磁共振成像(MRI)显示PRES的特征累及双侧外侧膝状体、海马体和脑干。膝状体后视觉通路,即顶枕叶皮质未受累。患者通过最佳血压控制后病情好转,5天后出院。

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