Obinero Chioma, Makar Gabriel S, Rowe Jean Sebastien, Makar Michael S, Holdbrook Thomas, Hageboutros Alexandre, Spitz Francis R, Kovacs James E
Cooper Medical School of Rowan University, 401 Broadway, Camden NJ 08103, USA.
Cooper University Hospital, Division of Body Imaging, Department of Radiology, 1 Cooper Plaza, Camden, NJ 08103, USA.
Radiol Case Rep. 2019 Feb 26;14(5):555-560. doi: 10.1016/j.radcr.2019.02.005. eCollection 2019 May.
Gastrointestinal stromal tumors (GISTs) are rare mesenchymal neoplasms, representing approximately 1%-2% of all primary gastrointestinal malignancies. Incidental GISTs are often less than 1 cm when discovered and have been reported predominantly in obese patients undergoing surgery for other medical indications. We present the rare case of a large incidental GIST in a nonobese patient with acutely symptomatic nephrolithiasis. Large GISTs may be treated with neoadjuvant imatinib mesylate to reduce tumor size prior to surgery, though some tumors may experience little change in size despite effective treatment. Treatment response for GISTs can be monitored via imaging studies, such as computed tomography or magnetic resonance imaging, but computed tomography is generally preferred over magnetic resonance imaging.
胃肠道间质瘤（GISTs）是罕见的间叶性肿瘤，约占所有原发性胃肠道恶性肿瘤的1%-2%。偶然发现的GISTs在被发现时通常小于1厘米，并且主要报道于因其他医学指征接受手术的肥胖患者中。我们报告了1例罕见的病例，一名非肥胖患者患有急性症状性肾结石，同时偶然发现了一个较大的GIST。较大的GISTs可在手术前用新辅助甲磺酸伊马替尼治疗以缩小肿瘤大小，尽管有些肿瘤在有效治疗后大小可能变化不大。GISTs的治疗反应可通过影像学检查进行监测，如计算机断层扫描或磁共振成像，但一般而言，计算机断层扫描比磁共振成像更受青睐。
