Jans Anne C H, Caumes Xavier, Reek Joost N H
Homogeneous, Supramolecular and Bio-Inspired Catalysis Van't Hoff Institute for Molecular Sciences University of Amsterdam Science Park 904 Amsterdam 1098 XH The Netherlands.
ChemCatChem. 2019 Jan 9;11(1):287-297. doi: 10.1002/cctc.201801399. Epub 2018 Oct 30.
Gold catalysis has experienced a tremendous development over the past decades, and is nowadays widely used in organic synthesis to perform chemical transformations of π-bond-containing molecules. Catalyst development has been based mostly on ligand development and counter-ion strategies. More recently, the encapsulation of gold catalysts in (supra)molecular cages was explored as a new way to control selectivity and reactivity of gold catalysts. In this review, we describe the cages that have been employed as hosts for gold complexes, along with their impact on the catalytic performance. Covalent and supramolecular approaches to encapsulate single metal complexes will be described and the impact on the catalytic performance will be discussed. Also, recent strategies to pre-organize multiple metal centers will be discussed.
在过去几十年中，金催化经历了巨大的发展，如今在有机合成中广泛用于对含π键分子进行化学转化。催化剂的开发主要基于配体开发和抗衡离子策略。最近，将金催化剂封装在（超）分子笼中作为控制金催化剂选择性和反应性的新方法得到了探索。在本综述中，我们描述了用作金配合物主体的笼状结构及其对催化性能的影响。将描述封装单金属配合物的共价和超分子方法，并讨论其对催化性能的影响。此外，还将讨论预组织多个金属中心的最新策略。
