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[Epidemiology of stroke and cerebral protection in patients undergoing transcatheter aortic valve replacement].

作者信息

Testa Luca, Pero Gaetano, Bollati Mario, Casenghi Matteo, Popolo Rubbio Antonio, Cuman Magdalena, Agnifili Mauro, Pizzocri Samuele, Bedogni Francesco

机构信息

Dipartimento di Cardiologia, IRCCS Policlinico S. Donato, San Donato Milanese (MI).

Dipartimento di Cardiologia, Policlinico Vittorio Emanuele, Università degli Studi, Catania.

出版信息

G Ital Cardiol (Rome). 2019 Mar;20(3 Suppl 1):17S-22S. doi: 10.1714/3121.31037.

Abstract

The introduction into clinical practice of transcatheter aortic valve implantation (TAVI) has led to a significant change in the therapeutic paradigm for patients with valvular aortic stenosis. However, in parallel with the benefits obtained in prognosis and quality of life, an inherent risk of major cerebral thromboembolic events has been observed. In different studies this risk has been estimated between 2% and 6%. In order to reduce the incidence of cerebrovascular accidents during TAVI, several brain protection systems have been developed but, to date, none has obtained sufficient clinical evidence to be implemented on a large scale, and they are therefore used only in selected cases. Furthermore, periprocedural drug therapy and follow-up are still the subject of extensive discussion in the scientific community. This paper reviews the topic of stroke prevention in patients undergoing TAVI for both the periprocedural and postprocedural aspects.

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