Menéndez Hernando Cristina, Chacón Aguilar Rocío, Fariñas Salto Mercedes, Pérez Crespo Rocío, Martin Molina Raquel, Moreno Novillo Rocío, Cabrerizo Ortiz María
Hospital Universitario Infanta Leonor, Madrid, España.
Arch Argent Pediatr. 2019 Apr 1;117(2):e142-e146. doi: 10.5546/aap.2019.e142.
Fetomaternal transfusion (FMT) is defined by the transfer of fetal blood into the maternal circulation. The incidence of massive FMT is estimated to be approximately 0.2-0.9 % of births. Although a number of etiologies have been associated with FMT, most causes remain unidentified and the pregnancy is usually asymptomatic. The most frequent symptom is the decrease in fetal movements (26 %) in relation to severe anemia. Several diagnostic modalities for FMT are described (Kleihauer stain, flow cytometry). We describe a case of a newborn with chronic anemia secondary to FMT who, after treatment with transfusions of red blood cells, presented volume overload and clinical worsening as a complication. In this case, our patient needed exchange transfusion for definitive improvement without disability.
胎儿-母体输血(FMT)定义为胎儿血液进入母体循环。大量FMT的发生率估计约为出生数的0.2-0.9%。尽管FMT与多种病因相关,但大多数病因仍不明,且妊娠通常无症状。最常见的症状是与严重贫血相关的胎动减少(26%)。描述了几种FMT的诊断方法(克来豪尔染色、流式细胞术)。我们报告一例因FMT继发慢性贫血的新生儿病例,该患儿在接受红细胞输血治疗后出现容量超负荷和临床病情恶化等并发症。在此病例中,我们的患者需要进行换血治疗以实现最终改善且不留残疾。