Ito Tomoyuki, Akazawa Satoshi, Ichikawa Yuichi, Yamamoto Yusuke, Aoyama Shohei, Kiuchi Tomoki, Nakao Junichi, Onitsuka Tetsuro, Araki Jun, Nakagawa Masahiro
Division of Plastic and Reconstructive Surgery, Shizuoka Cancer Center Hospital, Shizuoka, Japan.
Division of Head and Neck Surgery, Shizuoka Cancer Center Hospital, Shizuoka, Japan.
Plast Reconstr Surg Glob Open. 2019 Feb 5;7(2):e2109. doi: 10.1097/GOX.0000000000002109. eCollection 2019 Feb.
Perifascial areolar tissue (PAT) is a loose connective tissue on deep fascia, such as on the groin, thigh, or temporal region, which has abundant vascular plexus and mesenchymal stem cells. Nonvascularized PAT grafts can survive even on hypovascular wound beds. Therefore, PAT grafting is a possible alternative to conventional flap surgery to cover exposed bone or artifacts. In this article, we describe 2 cases of PAT grafting for the treatment of skin ulcers with exposed bone and artificial plate after mandible reconstruction. After negative-pressure wound therapy, PAT was used to covering exposed artificial plate for both cases, and a skin graft onto the PAT graft was performed in 1 case. The ulcers improved in both cases without recurrence. The gold-standard treatment of intractable ulcers and fistulas with an exposed tendon, bone, or artifact is coverage by a well-vascularized skin flap. However, PAT grafting has advantages in similar situations, occasionally together with skin grafting and/or negative-pressure wound therapy, because it is technically simple and less invasive.
筋膜周蜂窝组织(PAT)是一种位于深筋膜上的疏松结缔组织,如腹股沟、大腿或颞部区域,其具有丰富的血管丛和间充质干细胞。无血管化的PAT移植物即使在血供不足的伤口创面上也能存活。因此,PAT移植是一种可能替代传统皮瓣手术来覆盖外露骨或假体的方法。在本文中,我们描述了2例PAT移植治疗下颌骨重建术后伴有外露骨和人工钢板的皮肤溃疡的病例。在负压伤口治疗后,两例均采用PAT覆盖外露的人工钢板,其中1例在PAT移植物上进行了植皮。两例溃疡均改善且无复发。对于伴有外露肌腱、骨或假体的顽固性溃疡和瘘管,金标准治疗方法是采用血供良好的皮瓣覆盖。然而,PAT移植在类似情况下具有优势,偶尔可联合植皮和/或负压伤口治疗,因为其技术操作简单且侵入性较小。