Toia Marco, Stocchero Michele, Jinno Yohei, Wennerberg Ann, Becktor Jonas P, Jimbo Ryo, Halldin Anders
Int J Oral Maxillofac Implants. 2019 Mar/Apr;34(2):320-328. doi: 10.11607/jomi.6965.
To evaluate the effect of misfit at implant-level fixed partial dentures (ILFPDs) and marginal bone support on the generation of implant cracks.
This in vitro study included a mechanical fatigue test and finite element analysis. A mechanical cycling loading test was performed using 16 experimental models, each consisting of two parallel implants subdivided into four groups based on the misfit and the supporting bone condition. The framework, firmly seated at implants, was dynamically loaded vertically with a force of 1,600/160 N and 15 Hz for 1 × 10 cycles. Optical microscope, scanning electron microscope (SEM), and computed tomography three-dimensional (CT-3D) analyses were performed to detect impairments. Finite element models, representing the setups in the mechanical fatigue test, were used to represent the fatigue life.
None of the mechanical components presented distortion or fracture at the macroscopic level during the test. In a microscopy evaluation, the fatigue test revealed scratches visible in the inner part of the conical portion of the implants regardless of the groups. SEM and CT-3D analysis revealed one implant from the misfit/no bone loss group with a microfracture in the inner part of the conical interface. The simulated effective stress levels in the coronal body were higher in the misfit groups compared with the no misfit groups. The misfit groups presented effective stress levels, above 375 MPa, that penetrated the entire wall thickness. The no bone loss group presented an effective stress level above 375 MPa along its axial direction. In the no misfit group, the area presenting effective stress levels above 375 MPa in the conical connection was larger for the bone loss group compared with the no bone loss group.
This study confirmed that implant fracture is an unlikely adverse event. A clear pattern of effective distribution greater than fatigue limit stresses could be noticed when the misfit was present. The dynamic load simulation demonstrated that the crack is more likely to occur when implants are fully supported by marginal bone compared with a bone loss scenario. Within the limitations of this study, it is speculated that marginal bone loss might follow the appearance of an undetected crack. Further research is needed to develop safe clinical protocols with regard to ILFPD.
评估种植体水平固定局部义齿(ILFPD)的不匹配度及边缘骨支持对种植体裂纹产生的影响。
本体外研究包括机械疲劳试验和有限元分析。使用16个实验模型进行机械循环加载试验,每个模型由两个平行种植体组成,根据不匹配度和支持骨状况分为四组。将框架牢固地安装在种植体上,以1600/160 N的力和15 Hz的频率垂直动态加载1×10⁶ 次循环。进行光学显微镜、扫描电子显微镜(SEM)和计算机断层扫描三维(CT-3D)分析以检测损伤情况。使用代表机械疲劳试验设置的有限元模型来表示疲劳寿命。
在试验过程中,所有机械部件在宏观层面均未出现变形或断裂。在显微镜评估中,疲劳试验显示无论哪一组,种植体锥形部分内部均可见划痕。SEM和CT-3D分析显示,在不匹配/无骨吸收组中有一个种植体在锥形界面内部出现微骨折。与无不匹配组相比,不匹配组中种植体冠部的模拟有效应力水平更高。不匹配组的有效应力水平超过375 MPa,穿透了整个壁厚。无骨吸收组在其轴向方向上的有效应力水平超过375 MPa。在无不匹配组中,与无骨吸收组相比,骨吸收组在锥形连接处有效应力水平超过375 MPa的区域更大。
本研究证实种植体骨折是不太可能发生的不良事件。当存在不匹配时,可以注意到有效应力分布明显大于疲劳极限应力的模式。动态载荷模拟表明,与骨吸收情况相比,当种植体完全由边缘骨支持时,裂纹更有可能出现。在本研究的局限性内,推测边缘骨吸收可能在未检测到的裂纹出现之后发生。需要进一步研究以制定关于ILFPD的安全临床方案。