Gill Daniel M, Male Louise, Jones Alan M
School of Pharmacy, University of Birmingham, Edgbaston, B15 2TT, UK.
Chem Commun (Camb). 2019 Apr 9;55(30):4319-4322. doi: 10.1039/c9cc01057b.
The study of organosulfates is a burgeoning area in biology, yet there are significant challenges with their synthesis. We report the development of a tributylsulfoammonium betaine as a high yielding route to organosulfates. The optimised reaction conditions were interrogated with a diverse range of alcohols, including natural products and amino acids.
有机硫酸盐的研究是生物学中一个新兴领域，但其合成存在重大挑战。我们报道了一种三丁基磺基甜菜碱的开发，它是一种高产率合成有机硫酸盐的方法。我们用多种醇类对优化后的反应条件进行了研究，这些醇类包括天然产物和氨基酸。
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