冷球蛋白血症患者伴脾梗死的脾脏边缘区 B 细胞淋巴瘤。

Splenic Marginal Zone B-Cell Lymphoma With Splenic Infarction in a Patient With Cold Agglutinin Disease.

机构信息

Department of Radiology, Shiga General Hospital, Moriyama, Japan

Division of PET Imaging, Shiga Medical Center Research Institute, Moriyama, Japan

出版信息

Clin Nucl Med. 2019 May;44(5):e372-e374. doi: 10.1097/RLU.0000000000002528.

DOI:10.1097/RLU.0000000000002528

PMID:30888998

Abstract

We report a case of splenic marginal zone B-cell lymphoma discovered in a 73-year-old man with cold agglutinin disease. PET/CT revealed splenomegaly with focally intense uptake of F-FDG and diffusely increased bone marrow uptake, which was considered to be secondary to hemolytic anemia. Splenectomy was performed. The histopathology of the spleen showed splenic marginal zone B-cell lymphoma with partial splenic infarction, which correlated with the area of focal intense FDG uptake. Depending on the time since onset, splenic infarctions can present as focal FDG accumulation.

摘要

我们报告了一例冷自身免疫性溶血性贫血患者中发现的脾边缘区 B 细胞淋巴瘤。PET/CT 显示脾肿大，伴有局灶性 F-FDG 摄取增加和弥漫性骨髓摄取增加，这被认为是溶血性贫血的继发表现。行脾切除术。脾的组织病理学显示脾边缘区 B 细胞淋巴瘤伴部分脾梗死，与局灶性 FDG 摄取增加区域相关。根据发病时间的不同，脾梗死可表现为局灶性 FDG 聚集。