Department of Neurology, University Hospital, Ludwig-Maximilians-University, Munich, Germany.
Department of Neurology, University Hospital, Ludwig-Maximilians-University, Munich, Germany.
J Neurol Sci. 2019 May 15;400:32-33. doi: 10.1016/j.jns.2019.03.010. Epub 2019 Mar 14.
We describe the first case of a patient with brain abscesses caused by Stenotrophomonas maltophilia as a complication after motor cortex stimulator implantation. Brain abscesses pose a challenge in diagnosis and treatment, because microbiological diagnosis is not always achieved, antibiotic drugs may not penetrate well into the CNS and some bacteria have resistances to typical empirical antibiotic drugs. In this case diagnosis was only made after removal of the stimulator and a long term treatment with antibiotic drugs was necessary. As neurostimulation devices become more common, formerly rare bacteria may become a more common complication. Bacteria with biofilm properties and a problematic resistance spectrum like Stenotrophomonas maltophilia should be included in the differential diagnosis, because they will not respond to the typical empirical treatment.
我们描述了首例脑脓肿患者的病例,该患者是由于运动皮层刺激器植入后的并发症而导致嗜麦芽寡养单胞菌感染。脑脓肿在诊断和治疗方面带来了挑战,因为微生物学诊断并不总是能够实现,抗生素药物可能无法很好地渗透到中枢神经系统,并且某些细菌对典型的经验性抗生素药物具有耐药性。在这种情况下,只有在移除刺激器后才做出诊断,并且需要长期使用抗生素药物进行治疗。随着神经刺激设备变得越来越普遍,以前罕见的细菌可能会成为更常见的并发症。具有生物膜特性和问题耐药谱的细菌,如嗜麦芽寡养单胞菌,应纳入鉴别诊断,因为它们不会对典型的经验性治疗产生反应。