M.Sc. Dentistry Program, Ibirapuera University, Sao Paulo, SP, Brazil.
Unit of Basic Oral Investigation (UIBO), School of Dentistry, El Bosque University, Bogota, Colombia.
Periodontol 2000. 2019 Feb;79(1):81-106. doi: 10.1111/prd.12248.
The decision-making process for the treatment of recession-type defects is based on translation of the outcomes from randomized controlled trials and systematic reviews to clinical practice. Such an approach is capable of assisting researchers, clinicians, and patients to understand the mechanisms and effects of the treatment of different root-coverage procedures, as well as turning treatment options into usable and predictable tools to be applied in dental practice. This review explores: (a) the aspects related to the etiology of gingival recession; (b) the history of periodontal plastic surgery procedures used to achieve root coverage; (c) the main findings, implications of research, and practice of root-coverage procedures described from the current base of systematic reviews; (d) the role of the evidence produced in Latin American research centers; and (e) the outcomes of an individual patient data meta-analysis of randomized controlled trials evaluating the role of root coverage and restorative procedures in achieving complete root coverage of noncarious cervical lesions. The findings of the current base of evidence clearly indicate that all of the main periodontal plastic surgery procedures lead to improvements in initial clinical parameters, but subepithelial connective tissue grafts, either alone or associated with coronally advanced flaps, result in superior complete root coverage, long-term stability, and greater increase of keratinized tissue. Nonetheless, coronally advanced flaps, either associated with biomaterials (acellular dermal matrix grafts, enamel derivative proteins and xenogeneic collagen matrix) or used alone, provide satisfactory results and are suitable for use as secondary/alternative procedures to subepithelial connective tissue grafts.
治疗退缩型缺损的决策过程基于将随机对照试验和系统评价的结果转化为临床实践。这种方法能够帮助研究人员、临床医生和患者了解不同根覆盖程序的治疗机制和效果,并将治疗选择转化为可用于临床实践的可用且可预测的工具。本综述探讨了:(a) 牙龈退缩病因学相关方面;(b) 用于实现根覆盖的牙周整形手术史;(c) 从当前系统评价基础描述的根覆盖程序的主要发现、研究意义和实践;(d) 拉丁美洲研究中心产生的证据的作用;以及(e) 评价根覆盖和修复程序在非龋性颈病变完全根覆盖中的作用的随机对照试验个体患者数据荟萃分析的结果。现有证据基础的研究结果清楚地表明,所有主要的牙周整形手术都能改善初始临床参数,但上皮下结缔组织移植术(单独或与冠向推进瓣联合使用)可实现更好的完全根覆盖、长期稳定性和更大的角化组织增加。然而,冠向推进瓣(与生物材料[脱细胞真皮基质移植物、牙釉质衍生蛋白和异种胶原基质]联合使用或单独使用)可提供满意的结果,并且适合作为上皮下结缔组织移植术的次要/替代程序。