From the Research Center for Sectional and Imaging Anatomy (Z.L., F.X., Z.Z., X.L., S.L.), Institute of Brain and Brain-Inspired Science, Shandong University Cheeloo Medical College, Shandong, China.
Department of Medical Imaging (Z.Z., X.L.), Provincial Hospital Affiliated with Shandong University, Shandong, China.
AJNR Am J Neuroradiol. 2019 Apr;40(4):718-725. doi: 10.3174/ajnr.A6013. Epub 2019 Mar 20.
Few investigators have studied the lateral ventricle formation related to the development of the calcarine sulcus. Our purpose was to establish the relationship between the lateral ventricles and the calcarine sulcus in the second and third trimesters.
Fetal brain MR imaging (3T and 7T) was performed in 84 fetuses at 14-35 gestational weeks. The lateral ventricles and calcarine sulcus were 3D-reconstructed, and quantitative measurements were obtained.
The lateral ventricle volume decreases slowly at 14-23 gestational weeks and then increases rapidly at 24-35 gestational weeks. The depth and length of the calcarine sulcus develop with the increase in gestational weeks, leading to be squeezed in the lateral ventricle posterior horn. A linear correlation occurs between the calcarine sulcus length and posterior horn length: Right-length = 2.4204 (L) - 27.5706, Left-length = 2.0939 (L) - 23.4099.
The variation of lateral ventricle volume evolved from a slow to rapid increase at 14-35 gestational weeks. The shrinkage in the lateral ventricle posterior horn is accompanied by the development of the calcarine sulcus, resulting in a better linear correlation between the calcarine sulcus length and the posterior horn length. The present results are valuable in elucidating the evolution of lateral ventricle development and provide clues for the diagnosis of lateral ventricle abnormalities in the prenatal examination.
很少有研究人员研究过与距状沟发育相关的侧脑室形成。我们的目的是建立妊娠第 2 至 3 个三个月期间侧脑室与距状沟之间的关系。
对 84 例妊娠 14-35 周的胎儿进行了大脑磁共振成像（3T 和 7T）。对侧脑室和距状沟进行三维重建，并进行定量测量。
侧脑室容积在妊娠 14-23 周缓慢减少，然后在妊娠 24-35 周迅速增加。距状沟的深度和长度随着妊娠周数的增加而发育，导致其在侧脑室后角被挤压。距状沟长度与后角长度之间存在线性相关：右侧长度=2.4204（L）-27.5706，左侧长度=2.0939（L）-23.4099。
妊娠 14-35 周期间，侧脑室容积的变化由缓慢增加变为快速增加。侧脑室后角的缩小伴随着距状沟的发育，导致距状沟长度与后角长度之间的线性相关性更好。本研究结果有助于阐明侧脑室发育的演变过程，并为产前检查中侧脑室异常的诊断提供线索。
