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直视内镜下无X线监视放置消化道支架治疗消化道狭窄的疗效与安全性

[Efficacy and safety of digestive tract stent placement under direct visual endoscopy without X-ray monitoring in treatment of digestive tract stricture].

作者信息

Shen Hong, Ji Feng

机构信息

Department of Gastroenterology, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.

出版信息

Zhejiang Da Xue Xue Bao Yi Xue Ban. 2018 Dec 25;47(6):643-650. doi: 10.3785/j.issn.1008-9292.2018.12.13.

Abstract

OBJECTIVE

To evaluate the efficacy and safety of digestive tract stent implantation under direct visual endoscopy without X-ray monitoring in the treatment of digestive tract stricture.

METHODS

The clinical data of patients undergoing digestive tract stent placement under direct visual endoscopy without X-ray monitoring in the First Affiliated Hospital of Zhejiang University School of Medicine from March 2003 to November 2017 were retrospectively analyzed. The process of procedures, the postoperative complications and the postoperative follow-up data were documented. The survival time of patients with malignant gastrointestinal stricture was compared between those with and without stent implantation.

RESULTS

Among 562 patients, there were 310 cases of esophagus and cardia stricture, 40 cases of gastroduodenus stricture, 212 cases of colorectum stricture, and 63 cases with esophagus-tracheal fistula,esophagus-mediastinal fistula or anastomotic fistula. The stents were implanted successfully in 560 cases (99.64%) and the symptoms were alleviated in all patients after stent implantation (100%). Postoperative substernal discomfort, chest pain or abdominal pain occurred in 26 cases (4.64%), bleeding in 18 cases (3.21%), displacement of esophageal stents in 9 cases (1.61%), and restenosis in 15 cases (2.68%), in whom the stents were successfully placed again. None of the patients died within 7 days after the procedure. The incidence of postoperative abdominal pain, bleeding and stent displacement in esophageal/cardiac stricture patients was higher than that in the colorectal stricture patients (<0.05). In 284 cases of malignant stenosis, the median survival time of colorectal stricture patients[(27.5±1.94) months] was significantly higher than that of esophagus/cardia stricture patients[(13.40±0.71) months] and gastroduodenal stricture patients[(11.00±1.78) months]. The survival time of stenting patients with upper gastrointestinal malignant stenosis was significantly longer than that of the non-stenting patients (<0.05).

CONCLUSIONS

Stent implantation under direct visual endoscopy without X-ray monitoring is safe and effective for the treatment of benign and malignant stricture of digestive tract and closure of fistula.

摘要

目的

评估直视内镜下无X线监测的消化道支架置入术治疗消化道狭窄的有效性及安全性。

方法

回顾性分析2003年3月至2017年11月在浙江大学医学院附属第一医院接受直视内镜下无X线监测消化道支架置入术患者的临床资料,记录手术过程、术后并发症及术后随访数据,比较恶性胃肠道狭窄患者支架置入与未置入支架的生存时间。

结果

562例患者中,食管及贲门狭窄310例,胃十二指肠狭窄40例,结直肠狭窄212例,合并食管气管瘘、食管纵隔瘘或吻合口瘘63例。560例(99.64%)成功置入支架,所有患者置入支架后症状均缓解(100%)。术后26例(4.64%)出现胸骨后不适、胸痛或腹痛,18例(3.21%)出血,9例(1.61%)食管支架移位,15例(2.68%)再狭窄,均成功再次置入支架。术后7天内无患者死亡。食管/贲门狭窄患者术后腹痛、出血及支架移位发生率高于结直肠狭窄患者(<0.05)。284例恶性狭窄患者中,结直肠狭窄患者的中位生存时间[(27.5±1.94)个月]显著高于食管/贲门狭窄患者[(13.40±0.71)个月]和胃十二指肠狭窄患者[(11.00±1.78)个月]。上消化道恶性狭窄支架置入患者的生存时间显著长于未置入支架患者(<0.05)。

结论

直视内镜下无X线监测的支架置入术治疗消化道良恶性狭窄及瘘口封闭安全有效。

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