Division of Infectious Diseases, Duke University, Durham, North Carolina.
Divisions of Infectious Diseases & Organ Transplantation, Northwestern University Feinberg School of Medicine, Northwestern University Comprehensive Transplant Center, Chicago, Illinois.
Clin Transplant. 2019 Sep;33(9):e13547. doi: 10.1111/ctr.13547. Epub 2019 Apr 10.
These updated guidelines from the Infectious Diseases Community of Practice of the American Society of Transplantation will review the current state of the art of donor-derived infections. Specifically, the guideline will summarize standardized definitions and approaches to defining imputability, updated data on the epidemiology of donor-derived infections, and approaches to risk mitigation against transmission of infections. This update will additionally provide guidance on the use of HIV+ donors in HIV+ recipients, the use of HCV-viremic donors in non-viremic recipients, donors with endemic infections, and donors with bacteremia, meningitis, and encephalitis. Lastly, the guidance will summarize an approach to recipients with a suspected donor-derived infection.
这些由美国移植学会传染病实践社区更新的指南将回顾供体源性感染的最新技术现状。具体来说,该指南将总结供体源性感染的可归因性的标准化定义和方法,更新供体源性感染的流行病学数据,以及降低感染传播风险的方法。本更新还将提供关于在 HIV 阳性受者中使用 HIV 阳性供者、在非病毒血症受者中使用 HCV 病毒血症供者、携带地方性感染的供者以及携带菌血症、脑膜炎和脑炎的供者的指导意见。最后,该指南将总结怀疑供体源性感染的受者的处理方法。