Department of Neurological Surgery, Loyola University Medical Center, Maywood, Illinois, USA.
Department of Pathology, Loyola University Medical Center, Maywood, Illinois, USA.
World Neurosurg. 2019 Jun;126:619-623. doi: 10.1016/j.wneu.2019.02.243. Epub 2019 Mar 21.
Central nervous system abscesses frequently can be seen in the immunocompromised population and most commonly consist of intracranial collections in the adult patient. Spinal intradural abscesses are less commonly encountered, and there are even fewer numbers in the pediatric population with a concordant absence of documentation in the published literature.
In this case report, we describe the presentation of a 2-year-old boy with a history of perinatal Escherichia coli meningitis at 2.5 months of age who was found to have an intradural spinal lesion, initially concerning for neoplasm, but later confirmed as an E. coli abscess following biopsy. He was managed with surgical aspiration of the abscess and a long course of intravenous antibiotics. The patient was treated with antibiotics with repeat imaging studies that revealed residual abscess that required re-aspiration at a later date.
Here we present an unusual disease process with an unusual disease pathogenesis in a pediatric patient currently residing in a developed country.
中枢神经系统脓肿在免疫功能低下的人群中经常可见,最常见的是成年人颅内脓肿。硬脊膜内脊髓脓肿则较少见,儿童中更为罕见,且在已发表的文献中也鲜有相关记录。
在本病例报告中,我们描述了一名 2 岁男孩的临床表现,该男孩在出生后 2.5 个月时患有围产期大肠埃希菌脑膜炎,最初发现有硬脊膜内脊髓病变,最初怀疑为肿瘤,但后来通过活检证实为大肠埃希菌脓肿。他接受了脓肿抽吸术和长时间的静脉注射抗生素治疗。患者接受了抗生素治疗,并进行了多次影像学检查,结果显示仍有脓肿残留,后来需要再次抽吸。
我们在此介绍了一种在发达国家居住的儿童中不常见的疾病过程和发病机制。