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1998 - 2014年瑞士22个手术组围手术期死亡率的进展情况不明。

Uncertain progress in Swiss perioperative mortality 1998-2014 for 22 operation groups.

作者信息

Wacker Johannes, Zwahlen Marcel

机构信息

Institute of Anaesthesia and Intensive Care, Hirslanden Clinic, Zurich, Switzerland.

Institute of Social and Preventive Medicine (ISPM), University of Bern, Switzerland.

出版信息

Swiss Med Wkly. 2019 Mar 24;149:w20034. doi: 10.4414/smw.2019.20034. eCollection 2019 Mar 11.

Abstract

BACKGROUND

The perioperative mortality rate (POMR) is used as a quality indicator to monitor health care system performance at regional and national levels. The Swiss Federal Office of Public Health publishes national in-hospital mortality rates for several indicator conditions and indicator operation types (IORs). We investigated long-term time trends of POMRs from 1998-2014. In view of continual advances in perioperative care, we expected to find decreasing trends.

METHODS

Non-cardiosurgical IORs containing aggregated age- and sex-specific data (number of operations and deaths) for all years of the study period were included to calculate age-standardised POMRs using the 2013 European Standard Population. We assessed calendar time trends of POMRs using multivariable Poisson regression. We categorised IORs according to the type of time trend (decreasing, unchanged, or increasing incident rate ratio) and mean risk levels (age-adjusted POMR).

RESULTS

A total of 22 IORs were included, comprising 1,561,012 operations and 22,140 deaths (overall crude POMR 1.42%). POMR trends decreased for 6 IORs representing 26.8% of operations, remained unchanged for 13 IORs (56.9% of operations), and increased for 3 IORs (16.4% of operations). IOR categorisation according to POMR trends and to risk levels yielded four groups. (1) Decreasing POMR trends, low- to intermediate-risk IORs (age-adjusted POMR 0.2-2.2%): cholecystectomy; arterial pelvic/leg aneurysm or dissection operation; femoral neck fracture; trochanteric fractures; gastric, duodenal or jejunal ulcer resection; major pulmonary or bronchial resection. (2) Unchanged POMR trends, low-risk IORs (0.1-0.9%): transurethral resection of the prostate (TUR prostate); hernia repair without intestinal operation; hysterectomy; extracranial vascular operation; nephrectomy; amputation foot, non-traumatic. (3) Unchanged POMR trends, intermediate-risk IORs (1.7-3.8%): hernia repair with intestinal operation; gastric carcinoma resection; non-ruptured abdominal aortic aneurysm (open operation); arterial pelvic/leg thromboembolic operation; colorectal resection, pancreatic resection; complex oesophageal procedure. (4) Increasing POMR trends, low- to high-risk IORs (0.1-5.2%): hip endoprosthesis; cystectomy; amputation lower limb. Impact of sex on POMR: hysterectomy and TUR prostate comprised 19.7% of all operations; among the remaining operations, 68.5% showed significantly lower and 27.1% significantly higher POMRs in females. 4.4% showed no sex difference.

CONCLUSIONS

In Switzerland, in-hospital POMR trends from 1998-2014 were unchanged or even increasing for the majority of IORs (73% of included operations). Our analysis used age-standardisation but cannot account for changes in coding practices and organisation of healthcare delivery. POMR trends should be systematically monitored at the national level and used to guide priorities in national quality improvement strategies.

摘要

背景

围手术期死亡率(POMR)被用作一项质量指标,以监测地区和国家层面的医疗保健系统绩效。瑞士联邦公共卫生局公布了几种指标疾病和指标手术类型(IORs)的全国住院死亡率。我们调查了1998年至2014年POMRs的长期时间趋势。鉴于围手术期护理的持续进步,我们预期会发现下降趋势。

方法

纳入研究期间所有年份包含按年龄和性别分类汇总数据(手术例数和死亡例数)的非心脏外科IORs,使用2013年欧洲标准人口计算年龄标准化POMRs。我们使用多变量泊松回归评估POMRs的日历时间趋势。我们根据时间趋势类型(发病率比值下降、不变或上升)和平均风险水平(年龄调整后的POMR)对IORs进行分类。

结果

共纳入22种IORs,包括手术例数1,561,012例,死亡例数22,140例(总体粗POMR为1.42%)。6种IORs的POMR趋势下降,占手术例数的26.8%;13种IORs保持不变(占手术例数的56.9%);3种IORs上升(占手术例数的16.4%)。根据POMR趋势和风险水平对IORs进行分类产生了四组。(1)POMR趋势下降,低至中度风险IORs(年龄调整后的POMR为0.2 - 2.2%):胆囊切除术;动脉盆腔/腿部动脉瘤或夹层手术;股骨颈骨折;转子间骨折;胃、十二指肠或空肠溃疡切除术;大型肺部或支气管切除术。(2)POMR趋势不变,低风险IORs(0.1 - 0.9%):经尿道前列腺切除术(TUR前列腺);无肠道手术的疝修补术;子宫切除术;颅外血管手术;肾切除术;非创伤性足部截肢术。(3)POMR趋势不变,中度风险IORs(1.7 - 3.8%):有肠道手术的疝修补术;胃癌切除术;非破裂腹主动脉瘤(开放手术);动脉盆腔/腿部血栓栓塞手术;结直肠切除术、胰腺切除术;复杂食管手术。(4)POMR趋势上升,低至高风险IORs(0.1 - 5.2%):髋关节置换术;膀胱切除术;下肢截肢术。性别对POMR的影响:子宫切除术和TUR前列腺占所有手术的19.7%;在其余手术中,68.5%女性的POMR显著较低,27.1%显著较高。4.4%无性别差异。

结论

在瑞士,1998年至2014年大多数IORs(纳入手术的73%)的住院POMR趋势不变甚至上升。我们的分析采用了年龄标准化,但无法解释编码实践和医疗服务组织的变化。应在国家层面系统监测POMR趋势,并用于指导国家质量改进策略中的优先事项。

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