CD59血型系统的最新进展。
An update on the CD59 blood group system.
作者信息
Weinstock Christof, Anliker Markus, von Zabern Inge
机构信息
Head of the Immunohematology Laboratory, Institute for Clinical Transfusion Medicine and Immunogenetics, German Red Cross Blood Service.
Deputy Head of the Institute of Medical and Chemical Laboratory Diagnostics (ZIMCL), University Hospital Innsbruck, Innsbruck, Austria.
出版信息
Immunohematology. 2019 Jan;35(1):7-8.
This update of the CD59 blood group system (Weinstock C, Anliker M, von Zabern I. CD59: a long-known complement inhibitor has advanced to a blood group system. Immunohematology 2015;31:145-51) increases the number of reported patients with CD59 deficiency from 10 to 14. All of these 14 patients suffered from severe illness. Recently, a new variant allele was found in heterozygosity. Flow cytometry data suggest that this variant was expressed on the red blood cells of the propositus. Although additional alleles have been found, the CD59 system (International Society of Blood Transfusion system 35) continues to have one antigen.
CD59血型系统的这一更新内容（温斯托克C、安利克M、冯·扎伯恩I。CD59：一种早已为人所知的补体抑制剂已发展成为一个血型系统。免疫血液学2015；31：145 - 51）将报告的CD59缺乏症患者数量从10例增加到了14例。这14名患者均患有严重疾病。最近，发现了一个杂合的新变异等位基因。流式细胞术数据表明该变异体在先证者的红细胞上表达。尽管已发现了其他等位基因，但CD59系统（国际输血协会系统35）仍然只有一种抗原。
Zotero 插件