Dohbit Julius Sama, Meka Esther, Tochie Joel Noutakdie, Ze Myriam Mbia Koudo, Essiben Felix, Agbor Valirie Ndip, Nkeck Jan Rene, Foumane Pascal
Departement of Gynaecology and Obstetrics, Yaoundé Gynaeco-Obstetrics and Paediatric Hospital, Yaoundé, Cameroon.
Departement of Gynaecology and Obstetrics, Faculty of Medicine and Biomedical Sciences, University of Yaoundé 1, Yaoundé, Cameroon.
BMC Res Notes. 2019 Mar 25;12(1):166. doi: 10.1186/s13104-019-4199-y.
In Africa, 80% of women ingest traditional medicine (TM) during pregnancy. Although widely used in Cameroon, no study in has either demonstrated its safety or effectiveness. Hence, we sought to determine the effects of TM ingestions during the peri-partum period on maternal and foetal outcomes. A cohort study was conducted from January to April 2016 in two referral maternity departments of Cameroon. We consecutively enrolled all consenting parturients with gestational age above 28 weeks. We divided them into two groups; exposed and unexposed. The exposure studied was ingestion of TM within 72 h prior to delivery. Variables studied were socio-demographic characteristics, type and frequency of TM ingested and details of labour.
We enrolled a total of 603 parturients of whom 147 in the exposed group and 456 in the non-exposed group. The most frequently used TM were honey and Triumfetta pentandra A. Ingestion of TM in the peri-paritum period was associated with intra-partum vaginal bleeding, dystocic labour, tachysystole and uterine atony. No adverse neonatal outcome was observed. Overall, these findings could help guide the direction of future research into the safety and potential benefits of peri-partum TM use, as well as serving as a preliminary reference for counselling.
在非洲，80%的女性在孕期会摄入传统药物（TM）。尽管在喀麦隆广泛使用，但尚无研究证明其安全性或有效性。因此，我们试图确定围产期摄入传统药物对母婴结局的影响。2016年1月至4月在喀麦隆的两个转诊产科进行了一项队列研究。我们连续纳入了所有孕周超过28周且同意参与的产妇。我们将她们分为两组：暴露组和非暴露组。所研究的暴露因素是分娩前72小时内摄入传统药物。所研究的变量包括社会人口学特征、摄入传统药物的类型和频率以及分娩细节。
我们共纳入了603名产妇，其中暴露组147名，非暴露组456名。最常使用的传统药物是蜂蜜和刺蒴麻。围产期摄入传统药物与产时阴道出血、难产、子宫收缩过速和子宫收缩乏力有关。未观察到不良新生儿结局。总体而言，这些发现有助于指导未来对围产期使用传统药物的安全性和潜在益处的研究方向，并作为咨询的初步参考。
