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色素减退斑作为扁平苔藓和扁平毛发苔藓的表现

Hypopigmented Macules as Manifestation of Lichen Planus and Lichen Planopilaris.

作者信息

Arnold David, Hoffman Melissa B, Onajin Oluwakemi, Sangüeza Omar P, McMichael Amy

机构信息

Department of Dermatology, Wake Forest School of Medicine, Winston-Salem, NC.

Department of Dermatopathology, University of Chicago, Chicago, IL.

出版信息

Am J Dermatopathol. 2019 Jul;41(7):514-517. doi: 10.1097/DAD.0000000000001389.

Abstract

Lichen planus (LP) is an idiopathic inflammatory disease of the skin, hair, nails, and mucous membranes. Classic cutaneous LP is characterized by violaceous flat-topped papules that typically favor the extremities. LP on the scalp, otherwise known as lichen planopilaris, classically presents with scarring alopecia, perifollicular erythema and follicular prominence. Although LP pigmentosus presents primarily as hyperpigmentation, there is only one previous report of hypopigmented LP. In this report, the authors report 2 cases of LP that presented primarily as hypopigmented macules in 2 African American men. The first patient presented with hypopigmented macules on face and scalp as well as trunk and extremities. The second patient presented with hypopigmented macules on scalp with associated alopecia. Histopathological examination from both patients showed features of LP. The authors propose a new variant of LP that presents acutely as hypopigmented lesions.

摘要

扁平苔藓(LP)是一种皮肤、毛发、指甲和黏膜的特发性炎症性疾病。典型的皮肤扁平苔藓的特征是紫罗兰色扁平丘疹,通常好发于四肢。头皮部扁平苔藓,又称扁平毛发苔藓,典型表现为瘢痕性脱发、毛囊周围红斑和毛囊突出。尽管色素性扁平苔藓主要表现为色素沉着,但之前仅有一例色素减退性扁平苔藓的报道。在本报告中,作者报告了2例主要表现为色素减退斑的扁平苔藓病例,患者为2名非裔美国男性。首例患者面部、头皮以及躯干和四肢出现色素减退斑。第二例患者头皮出现色素减退斑并伴有脱发。两名患者的组织病理学检查均显示扁平苔藓的特征。作者提出了一种新的扁平苔藓变体,其急性表现为色素减退性皮损。

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