IEEE Trans Ultrason Ferroelectr Freq Control. 2019 Jul;66(7):1158-1169. doi: 10.1109/TUFFC.2019.2908831. Epub 2019 Apr 2.
Recent advances in ultrafast contrast imaging have facilitated innovations, such as superresolution imaging and ultrafast contrast-enhanced Doppler imaging. Combining plane and diverging wave imaging (PWI/DWI) with tissue harmonic imaging (THI) may offer improvements in image quality in applications such as 3-D THI and harmonic color flow. However, no studies have reported simulations of the nonlinear acoustic fields produced by diagnostic arrays in either plane or diverging wave mode. The aim of this study is to model three typical diagnostic arrays that are used in clinical practice and research, Verasonics L11-4v linear array, C5-2v convex array, and P4-2v phased array with the Khokhlov-Zabolotskaya-Kuznetsov (KZK) equation. We have two specific objectives: first, to investigate whether there is increased bubble destruction due to the nature of the plane and diverging fields in contrast imaging; and second, to investigate the feasibility of combining PWI/DWI and THI by quantifying the second harmonic generated by these fields. We showed in linear simulations that using such arrays for ultrafast contrast imaging produced pressures that are greater in the near field and lower in the far field than those of focused beams and thus may induce more near-field bubble destruction. In nonlinear simulations, the second harmonic produced by ultrafast THI was found to be 2-16 dB lower than that of focused beams for all arrays considered when operated at the same MI. This moderate difference of the second harmonic between PWI/DWI and focused ultrasound suggests that it is feasible to combine PWI/DWI and THI.
近年来,超快对比成像技术的发展促进了创新,如超分辨率成像和超快对比增强多普勒成像。将平面波和发散波成像(PWI/DWI)与组织谐波成像(THI)相结合,可能会提高 3D-THI 和谐波彩色血流等应用中的图像质量。然而,目前还没有研究报道在平面波或发散波模式下,诊断换能器阵产生的非线性声场的模拟。本研究的目的是用 Khokhlov-Zabolotskaya-Kuznetsov(KZK)方程对三种典型的临床和研究中使用的诊断换能器阵进行建模,它们是 Verasonics L11-4v 线性阵、C5-2v 凸阵和 P4-2v 相控阵。我们有两个具体目标:首先,研究在对比成像中,由于平面波和发散波的性质,是否会增加气泡的破坏;其次,通过量化这些声场产生的二次谐波,研究 PWI/DWI 和 THI 相结合的可行性。我们在线性模拟中表明,在超快对比成像中使用这些换能器阵会产生比聚焦波束更大的近场压力和更低的远场压力,因此可能会导致更多的近场气泡破坏。在非线性模拟中,当以相同的 MI 操作时,我们发现所有考虑的换能器阵产生的超快 THI 的二次谐波比聚焦波束低 2-16dB。PWI/DWI 和聚焦超声之间二次谐波的这种适度差异表明,将 PWI/DWI 和 THI 相结合是可行的。