Shah Muhammad Ijaz, Yang Zhening, Li Yao, Jiang Liming, Ling Jun
MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027, China.
Polymers (Basel). 2017 Oct 27;9(11):559. doi: 10.3390/polym9110559.
Novel biodegradable multiblock copolymers of [PCL--P(THF--CL)] with PCL fractions of 53.3 and 88.4 wt % were prepared by Janus polymerization of ε-caprolactone (CL) and tetrahydrofuran (THF). Their electrospun mats were obtained with optimized parameters containing bead-free nanofibers whose diameters were between 290 and 520 nm. The mechanical properties of the nanofiber scaffolds were measured showing the tensile strength and strain at break of 8⁻10 MPa and 123⁻161%, respectively. Annealing improved their mechanical properties and their tensile strength and strain at break of the samples increased to 10⁻13 MPa and 267⁻338%, respectively. Due to the porous structure and crystallization in nanoscale confinement, the mechanical properties of the nanofiber scaffolds appeared as plastics, rather than as the elastomers observed in bulk thermal-molded film.
通过ε-己内酯（CL）和四氢呋喃（THF）的雅努斯聚合反应制备了新型可生物降解的[PCL-P(THF-CL)]多嵌段共聚物，其PCL含量分别为53.3 wt%和88.4 wt%。通过优化参数获得了其电纺垫，其中包含无珠纳米纤维，直径在290至520纳米之间。对纳米纤维支架的力学性能进行了测量，结果表明其拉伸强度和断裂应变分别为8-10兆帕和123-161%。退火改善了它们的力学性能，样品的拉伸强度和断裂应变分别增加到10-13兆帕和267-338%。由于纳米尺度受限下的多孔结构和结晶，纳米纤维支架的力学性能表现为塑料，而不是在本体热成型薄膜中观察到的弹性体。
