影响人类供体眼结膜拭子污染率的供体相关因素
Donor-Dependent Factors Influencing Contamination Rates of Conjunctival Swabs of Human Donor Eyes.
作者信息
Röck Tobias, Blumenstock Gunnar, Bartz-Schmidt Karl Ulrich, Bramkamp Matthias, Landenberger Johanna, Röck Daniel
机构信息
Centre for Ophthalmology, University of Tübingen, Tübingen, Germany.
Institute for Clinical Epidemiology and Applied Biometry, University of Tübingen, Tübingen, Germany.
出版信息
Ann Transplant. 2019 Apr 10;24:191-198. doi: 10.12659/AOT.912266.
BACKGROUND This study investigated the effect of donor-dependent factors on contamination rates of conjunctival swabs of human donor eyes. MATERIAL AND METHODS From July 2015 to September 2017 a total of 1008 conjunctival swabs from 504 consecutive human donor eyes were analyzed. Cross-tabulation, chi-squared tests, and Fisher's exact tests were used to evaluate the effect of donor-dependent factors on contamination rates of conjunctival swabs. RESULTS The mean conjunctival swabs contamination rate was 28.4%. Donors with the diagnosis of carcinoma or metastases were associated with an increased conjunctival swab contamination rate [odds ratio (OR)=1.8, 95% confidence interval (CI)=1.2-2.6, p=0.007; OR=1.7, 95% CI=1.1-2.6, p=0.016; respectively]. However, the age, sex, diagnosis of diabetes mellitus, and donors who received chemotherapy did not significantly increase the conjunctival swab contamination risk. CONCLUSIONS Donors with the diagnosis of a carcinoma or metastases seemed to be predisposed to increased conjunctival swab contamination risk.
背景 本研究调查了供体相关因素对人类供体眼结膜拭子污染率的影响。
材料与方法 2015年7月至2017年9月，对来自504例连续人类供体眼的总共1008份结膜拭子进行了分析。采用交叉表、卡方检验和Fisher精确检验来评估供体相关因素对结膜拭子污染率的影响。
结果 结膜拭子的平均污染率为28.4%。诊断为癌症或转移瘤的供体与结膜拭子污染率升高相关[优势比(OR)=1.8，95%置信区间(CI)=1.2 - 2.6，p = 0.007；OR = 1.7，95% CI = 1.1 - 2.6，p = 0.016；分别]。然而，年龄、性别、糖尿病诊断以及接受化疗的供体并未显著增加结膜拭子的污染风险。
结论 诊断为癌症或转移瘤的供体似乎易患结膜拭子污染风险增加。
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