Antimicrobial Defense Lab, The Francis Crick Institute, London.
Cell Host Microbe. 2019 Apr 10;25(4):477-479. doi: 10.1016/j.chom.2019.03.014.
In this issue of Cell Host & Microbe, Thanabalasuriar et al. (2019) show how neutrophils and biofilm-forming bacteria respond reciprocally, resulting in the formation of a barricade comprised of neutrophil extracellular traps. Disrupting this exchange and the resulting barrier can be detrimental unless balanced in favor of the immune system.
在本期《细胞宿主与微生物》中,Thanabalasuriar 等人(2019)展示了中性粒细胞和生物膜形成细菌如何相互响应,导致由中性粒细胞细胞外陷阱组成的屏障的形成。除非这种交换和由此产生的屏障有利于免疫系统,否则破坏这种交换和由此产生的屏障可能是有害的。