Kitahara Hiroto, Raikhelkar Jayant, Kim Gene, Sarswat Nitasha, Sayer Gabriel, Uriel Nir, Song Tae, Onsager David, Jeevanandam Valluvan, Ota Takeyoshi
Department of Surgery, Section of Cardiac and Thoracic Surgery, The University of Chicago Medicine, 5841 S. Maryland Ave., MC 5040, Chicago, IL, 60637, USA.
Department of Medicine, Section of Cardiology, The University of Chicago Medicine, Chicago, IL, USA.
J Artif Organs. 2019 Sep;22(3):181-187. doi: 10.1007/s10047-019-01102-w. Epub 2019 Apr 11.
This is a single-center retrospective study to summarize clinical outcomes of patients requiring surgical continuous-flow left ventricular assist device (HeartMate II) exchange. The patients who underwent HeartMate II exchange were divided into two groups either via a subcostal approach (SC group) or a full sternotomy (FS group). The exclusion criteria of a subcostal approach for device exchange included the presence of outflow graft obstruction, and/or the need for concomitant cardiac procedures. Among 277 consecutive patients who underwent HeartMate II implantation from July 2008 to December 2015, 25 patients (9.0%) required device exchange (SC group; N = 13, FS group; N = 12). The SC group, compared to the FS group, had a shorter operative time (200.6 ± 31.4 min vs 534.2 ± 123.9 min; P < 0.001), shorter cardiopulmonary bypass time (33.1 ± 22.0 min vs 151.5 ± 53.1 min; P < 0.001), fewer blood transfusion (0.31 ± 0.48 units vs 4.67 ± 3.65 units; P = 0.002). The SC group had lower incidence of postoperative prolonged intubation (> 24 h) (7.7% vs 90.9%, P < 0.001), tracheostomy (0.0% vs 41.7%, P = 0.015), acute kidney injury requiring dialysis (0.0% vs 33.3%, P = 0.039). In-hospital mortality was 0.0% (0/13) in the SC group and 16.7% (2/12) in the FS group (P = 0.220). In conclusion, a subcostal approach was associated with shorter operative time, fewer blood transfusions, and less postoperative complications, compared to full sternotomy. A subcostal approach, if feasible, is preferred for HeartMate II device exchange.
这是一项单中心回顾性研究,旨在总结需要进行手术更换连续流左心室辅助装置(HeartMate II)的患者的临床结局。接受HeartMate II更换的患者通过肋下途径(SC组)或全胸骨切开术(FS组)分为两组。装置更换采用肋下途径的排除标准包括存在流出道移植物梗阻和/或需要同期进行心脏手术。在2008年7月至2015年12月期间连续接受HeartMate II植入的277例患者中,25例(9.0%)需要进行装置更换(SC组;N = 13,FS组;N = 12)。与FS组相比,SC组的手术时间更短(200.6±31.4分钟对534.2±123.9分钟;P < 0.001),体外循环时间更短(33.1±22.0分钟对151.5±53.1分钟;P < 0.001),输血次数更少(0.31±0.48单位对4.67±3.65单位;P = 0.002)。SC组术后长时间插管(>24小时)的发生率较低(7.7%对90.9%,P < 0.001),气管切开术的发生率较低(0.0%对41.7%,P = 0.015),需要透析的急性肾损伤的发生率较低(0.0%对33.3%,P = 0.039)。SC组的院内死亡率为0.0%(0/13),FS组为16.7%(2/12)(P = 0.220)。总之,与全胸骨切开术相比,肋下途径与更短的手术时间、更少的输血次数和更少的术后并发症相关。如果可行,HeartMate II装置更换首选肋下途径。