Preoperative C-reactive protein/albumin ratio predicts outcome of surgical papillary renal cell carcinoma.

: To evaluate the prognostic values of some preoperative inflammation-based factors including C-reactive protein/albumin ratio (CRP/Alb) and platelet level in papillary renal cell carcinoma (PRCC). A total of 108 PRCC patients underwent partial or radical nephrectomy were retrospectively analyzed. The prognostic values were determined with Kaplan-Meier analysis, univariate and multivariate COX regression models. CRP/Alb and platelet level were both significantly associated with subtype, Fuhrman grade, tumor stage, lymph node invasion, perinephric fat extension, shorter overall survival (OS) and disease-free survival (all p < 0.01). Further, CRP/Alb was an independent prognostic factor for OS (hazard ratio: 9.64, 95% CI: 2.17-23.78; p = 0.003). Relatively higher CRP/Alb independently predicted poorer OS of surgical PRCC patients.