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前尿道狭窄管理的最新进展。

Update on managing anterior urethral strictures.

作者信息

Fuehner Constantin, Dahlem Roland, Fisch Margit, Vetterlein Malte W

机构信息

Department of Urology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

出版信息

Indian J Urol. 2019 Apr-Jun;35(2):94-100. doi: 10.4103/iju.IJU_52_19.

Abstract

A number of techniques have been described for managing anterior urethral strictures in men. In this review, we aimed to summarize contemporary considerations regarding the holistic management of such strictures. The efficacy of reported outcomes is compared to provide evidence-based treatment recommendations. For anterior urethral strictures, durable long-term success rates of >90% may be achieved if the procedure is performed in capable hands at a high-volume referral center, even in recurrent strictures after previous open reconstruction. A one-stage urethroplasty is preferable to avoid a protracted treatment course with multiple interventions after dilation and direct vision internal urethrotomy. Staged urethroplasties are useful in complex anterior strictures providing durable success rates. In addition, perineal urethrostomy represents a valid last resort option with sufficient objective and subjective results. A follow-up evaluation should incorporate objective assessments such as radiographic and functional diagnostics as well as subjective, validated, and disease-specific patient-reported outcome measurement tools to allow for a better comparability and to improve individual risk prediction.

摘要

已经描述了多种治疗男性前尿道狭窄的技术。在本综述中,我们旨在总结有关此类狭窄整体管理的当代考量因素。比较报告结果的疗效,以提供基于证据的治疗建议。对于前尿道狭窄,如果在高容量转诊中心由经验丰富的医生进行手术,即使是在先前开放重建术后复发的狭窄,也可实现超过90%的持久长期成功率。一期尿道成形术更可取,以避免在扩张和直视下尿道内切开术后进行多次干预的漫长治疗过程。分期尿道成形术对复杂的前尿道狭窄有用,可提供持久的成功率。此外,会阴尿道造口术是一种有效的最后手段选择,具有足够的客观和主观效果。随访评估应纳入影像学和功能诊断等客观评估,以及主观、经过验证且针对特定疾病的患者报告结局测量工具,以实现更好的可比性并改善个体风险预测。

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