Agarwalla Avinesh, Gowd Anirudh K, Liu Joseph N, Garcia Grant H, Bohl Daniel D, Verma Nikhil N, Forsythe Brian
Midwest Orthopaedics at Rush, Rush University Medical Center, Chicago, Illinois, USA.
Department of Orthopaedic Surgery, Loma Linda University Medical Center, Loma Linda, California, USA.
Orthop J Sports Med. 2019 Feb 19;7(2):2325967118825453. doi: 10.1177/2325967118825453. eCollection 2019 Feb.
A longer operative time has been previously recognized as a risk factor for short-term complications after various orthopaedic procedures; however, it has yet to be investigated as an independent risk factor for postoperative complications after anterior cruciate ligament (ACL) reconstruction.
To identify whether a longer operative time in ACL reconstruction is an independent risk factor for the development of postoperative complications, hospital readmissions, or an extended length of stay within 30 days of the index procedure.
Descriptive epidemiology study.
Patients undergoing ACL reconstruction between 2005 and 2016 were identified using the American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) database. Cases with concomitant procedures were excluded from the analysis. We evaluated the association between operative time and preoperative variables such as patient age, sex, body mass index, comorbidities, and procedure. Correlations between adverse events and operative time, while controlling for the above preoperative variables, were calculated using multivariate Poisson regression with robust error variance.
A total of 14,159 procedures were included in this investigation. The mean patient age was 32.6 ± 10.8 years, the mean body mass index was 27.7 ± 6.5 kg/m, and the mean operative time was 89.7 ± 28.6 minutes. Patients who were between the ages of 18 and 30 years (mean operative time, 95.1 ± 27.8 minutes; relative risk [RR], 17.7; < .001), male (mean operative time, 91.9 ± 28.3 minutes; RR, 4.7; < .001), and nondiabetic (mean operative time, 89.8 ± 28.6 minutes; RR, 7.1; = .011) were associated with a longer operative duration. The overall complication rate was 1.1%. After adjusting for demographic characteristics and procedures, 15-minute incremental increases in operative duration were associated with an increased risk of deep vein thrombosis (RR, 1.12; = .042), surgical site infections (RR, 1.21; = .001), and sepsis (RR, 1.66; < .001) as well as increased readmission rates (RR, 1.23; = .001) and an extended length of stay (RR, 1.18; = .008).
While the overall adverse risk rate after ACL reconstruction remains low, marginal increases in operative time are associated with an increased risk of adverse events such as deep vein thrombosis, surgical site infections, sepsis, an extended length of stay, and readmissions. Thus, the operating physician and surgical staff should make all efforts to coordinate and prepare for each case to maximize surgical efficiency.
手术时间延长先前已被认为是各种骨科手术后短期并发症的一个风险因素;然而,它作为前交叉韧带(ACL)重建术后并发症的独立风险因素尚未得到研究。
确定ACL重建手术时间延长是否是术后并发症发生、再次入院或在初次手术30天内住院时间延长的独立风险因素。
描述性流行病学研究。
使用美国外科医师学会国家外科质量改进计划(ACS-NSQIP)数据库识别2005年至2016年期间接受ACL重建的患者。分析中排除了同期进行其他手术的病例。我们评估了手术时间与术前变量之间的关联,如患者年龄、性别、体重指数、合并症和手术方式。在控制上述术前变量的同时,使用具有稳健误差方差的多变量泊松回归计算不良事件与手术时间之间的相关性。
本研究共纳入14159例手术。患者平均年龄为32.6±10.8岁,平均体重指数为27.7±6.5kg/m²,平均手术时间为89.7±28.6分钟。年龄在18至30岁之间的患者(平均手术时间,95.1±27.8分钟;相对风险[RR],17.7;P<0.001)、男性(平均手术时间,91.9±28.3分钟;RR,4.7;P<0.001)和非糖尿病患者(平均手术时间,89.8±28.6分钟;RR,7.1;P=0.011)与较长的手术持续时间相关。总体并发症发生率为1.1%。在调整人口统计学特征和手术方式后,手术持续时间每增加15分钟,深静脉血栓形成风险增加(RR,1.12;P=0.042)、手术部位感染风险增加(RR,1.21;P=0.001)、脓毒症风险增加(RR,1.66;P<0.001),以及再次入院率增加(RR,1.23;P=0.001)和住院时间延长(RR,1.18;P=0.008)。
虽然ACL重建术后总体不良风险率仍然较低,但手术时间的微小增加与深静脉血栓形成、手术部位感染、脓毒症、住院时间延长和再次入院等不良事件风险增加相关。因此,手术医生和手术团队应尽一切努力为每个病例做好协调和准备,以最大限度提高手术效率。