From the Department of Internal Medicine, University of Michigan, Ann Arbor, MI.
Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, MI.
Cardiol Rev. 2020 Jan/Feb;28(1):14-19. doi: 10.1097/CRD.0000000000000253.
Pregnancy is a time of significant hemodynamic, metabolic, and hormonal stress that can unmask underlying subclinical cardiovascular abnormalities, and pregnancy-related complications may serve as early warning signs for future risk of cardiovascular disease. The increased recognition of these sex-specific risk factors could identify women who may benefit from more intensive risk factor modification to reduce morbidity and mortality later in life. In this review, we describe several pregnancy-related complications that have been associated with the risk of cardiovascular disease, including hypertensive disorders of pregnancy, gestational diabetes mellitus, preterm delivery, and pregnancy loss. Pregnancy-associated risk factors must be identified to fully assess a woman's future cardiovascular risk and may influence strategies for risk reduction.
妊娠是一个重大的血流动力学、代谢和激素应激时期，可能会揭示潜在的亚临床心血管异常，而与妊娠相关的并发症可能是未来心血管疾病风险的早期预警信号。对这些特定于性别的危险因素的认识增加，可以确定哪些女性可能受益于更强化的危险因素改变，以降低以后生活中的发病率和死亡率。在这篇综述中，我们描述了几种与心血管疾病风险相关的与妊娠相关的并发症，包括妊娠高血压疾病、妊娠期糖尿病、早产和流产。必须识别与妊娠相关的危险因素，以充分评估女性未来的心血管风险，并可能影响降低风险的策略。
