[热处理对结核菌素结构和生物学特性的影响]
[Effect of thermal treatment on the structure and biological properties of tuberculin].
作者信息
Ivanov M V, Lianda-Geller B A, Morozova A D, Pirogov V S, Samsonov G V
出版信息
Prikl Biokhim Mikrobiol. 1986 Nov-Dec;22(6):806-9.
PMID:3101059
Abstract
The effect of heat treatment used in the course of tuberculin production by Mycobacteria tuberculosis cells on the structure and biological activity of tuberculin was studied. Methods of preparative and analytical gel-filtration were used. The largest quantity of the biologically active component was obtained after 2-hour heat treatment of the mycobacteria culture.
摘要
研究了结核分枝杆菌细胞生产结核菌素过程中所采用的热处理对结核菌素结构和生物活性的影响。使用了制备性和分析性凝胶过滤方法。对分枝杆菌培养物进行2小时热处理后获得了最大量的生物活性成分。
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