Bergmann Michèle, Ballin Anne, Schulz Bianka, Dörfelt René, Hartmann Katrin
Medizinische Kleintierklinik, Ludwig-Maximilians-Universität München.
Tierarztl Prax Ausg K Kleintiere Heimtiere. 2019 Apr;47(2):98-109. doi: 10.1055/a-0870-0801. Epub 2019 Apr 23.
The main causative agents of feline upper respiratory tract disease (FURTD) are feline herpesvirus-1 (FHV-1) and feline calicivirus (FCV). These viral infections are common, especially in multiple cat households. Severely affected cats often need to be hospitalized. Intensive symptomatic therapy is important in the management of cats with FURTD. The use of antiviral drugs is limited in cats, as they are often ineffective or toxic when given systemically. Antiviral drugs are, therefore, mainly used locally for the treatment of FHV-1-associated eye changes. Famciclovir, however, is an effective drug for systemic therapy in cats with FHV-1-related clinical signs. For FCV, only few antiviral drugs are available. In a controlled study, the use of immunoglobulins in cats with FHV-1 and/or FCV infection reduced clinical signs of FURTD significantly faster.
猫上呼吸道疾病(FURTD)的主要致病原是猫疱疹病毒1型(FHV-1)和猫杯状病毒(FCV)。这些病毒感染很常见,尤其是在多猫家庭中。严重受影响的猫通常需要住院治疗。强化对症治疗在FURTD猫的管理中很重要。抗病毒药物在猫中的使用有限,因为全身性给药时它们往往无效或有毒。因此,抗病毒药物主要用于局部治疗与FHV-1相关的眼部病变。然而,泛昔洛韦是一种对出现FHV-1相关临床症状的猫进行全身治疗的有效药物。对于FCV,可用的抗病毒药物很少。在一项对照研究中,对感染FHV-1和/或FCV的猫使用免疫球蛋白能显著更快地减轻FURTD的临床症状。