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新型正电子发射断层显像(PET)诊断剂及相关治疗性放射性药物介绍。

An Introduction to Newer PET Diagnostic Agents and Related Therapeutic Radiopharmaceuticals.

作者信息

Mantel Ellie, Williams Jessica

机构信息

Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania; and

Molecular Imaging Department, Harley Street Clinic, HCA Healthcare, London, England.

出版信息

J Nucl Med Technol. 2019 Sep;47(3):203-209. doi: 10.2967/jnmt.118.224022. Epub 2019 Apr 24.

Abstract

With new radiopharmaceuticals constantly in development, the field of nuclear medicine is ever evolving. This continuing education article reviews some of the newer, less frequently used radiopharmaceuticals for PET diagnostic imaging and related therapeutic protocols. The radiopharmaceuticals discussed include U.S. Food and Drug Administration-approved tracers as well as tracers that are in clinical trials and have yet to obtain Food and Drug Administration approval. This article contains straightforward information on each tracer discussed, including disease process imaged or treated, half-life, energy, primary uses, basic protocols, distribution, and side effects. Although not all tracers may be available in rural locations, this information can be helpful in determining future patient-care offerings.

摘要

随着新型放射性药物不断研发,核医学领域也在持续发展。这篇继续教育文章回顾了一些用于PET诊断成像及相关治疗方案的较新的、较少使用的放射性药物。所讨论的放射性药物包括美国食品药品监督管理局批准的示踪剂以及正在进行临床试验且尚未获得食品药品监督管理局批准的示踪剂。本文包含了关于每种所讨论示踪剂的直接信息,包括成像或治疗的疾病过程、半衰期、能量、主要用途、基本方案、分布及副作用。尽管并非所有示踪剂在农村地区都可获取,但这些信息有助于确定未来的患者护理服务。

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