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评估黑色素瘤患者的腹腔镜腹股沟淋巴结清扫术。

Evaluation of the videoscopic inguinal lymphadenectomy in melanoma patients.

机构信息

Department of Surgical Oncology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.

出版信息

Eur J Surg Oncol. 2019 Sep;45(9):1712-1716. doi: 10.1016/j.ejso.2019.04.018. Epub 2019 Apr 25.

Abstract

INTRODUCTION

A completion or therapeutic inguinal lymph node dissection is a procedure accompanied with a high rate of postoperative complications. A novel, minimally invasive alternative has been developed; the videoscopic inguinal lymphadenectomy. The aim of this study is to present our first experience with the videoscopic inguinal lymphadenectomy among melanoma patients with inguinal metastases.

METHODS

Melanoma patients with a histologically confirmed inguinal metastases who underwent a videoscopic inguinal lymphadenectomy between November 2015 and January 2018 were included. Outcome measures were operation time, nodal yield, and postoperative complications. Furthermore, lymphedema measurements were performed both subjectively and objectively.

RESULTS

A total of 20 patients (3 males and 17 females) underwent a videoscopic inguinal lymphadenectomy. In 75% of patients the procedure was combined with an open iliac lymphadenectomy. Median operation time of the videoscopic procedure was 110 min (range, 79-165). There were no perioperative complications or conversions. In 12 patients (60%) there was ≥1 postoperative complication. The most frequent complications were seroma and wound infection. All complications were treated conservatively without the need for a surgical re-intervention. The median nodal yield of the videoscopic procedure was 9 (range, 1-19). Lymphedema was present in nine patients (45%) after three months of follow-up.

CONCLUSION

Our initial results show that the videoscopic inguinal lymphadenectomy is an attractive alternative to the conventional open technique. The number of complications is comparable with the complication rate reported for the conventional open procedure, but they are less severe and there is no need for a surgical re-intervention.

摘要

引言

完成或治疗性腹股沟淋巴结清扫术是一种伴随高术后并发症发生率的手术。已经开发出一种新的微创替代方法,即腹腔镜腹股沟淋巴结切除术。本研究旨在介绍我们在有腹股沟转移的黑色素瘤患者中进行腹腔镜腹股沟淋巴结切除术的初步经验。

方法

纳入 2015 年 11 月至 2018 年 1 月期间接受腹腔镜腹股沟淋巴结切除术的经组织学证实有腹股沟转移的黑色素瘤患者。主要观察指标是手术时间、淋巴结检出量和术后并发症。此外,还进行了主观和客观的淋巴水肿测量。

结果

共有 20 例患者(3 例男性,17 例女性)接受了腹腔镜腹股沟淋巴结切除术。在 75%的患者中,该手术与开放性髂腹股沟淋巴结切除术联合进行。腹腔镜手术的中位手术时间为 110 分钟(范围为 79-165 分钟)。无围手术期并发症或中转开腹。12 例患者(60%)术后至少有 1 种并发症。最常见的并发症是血清肿和伤口感染。所有并发症均经保守治疗,无需再次手术干预。腹腔镜手术的中位淋巴结检出量为 9 枚(范围为 1-19 枚)。术后 3 个月,9 例患者(45%)出现淋巴水肿。

结论

我们的初步结果表明,腹腔镜腹股沟淋巴结切除术是传统开放手术的一种有吸引力的替代方法。并发症的数量与传统开放手术报道的并发症发生率相当,但严重程度较轻,且无需再次手术干预。

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