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资源有限环境下儿童间质性肺疾病的诊治方法

Approach to childhood interstitial lung disease in resource limited setting.

作者信息

Vekaria-Hirani Varsha, Waris Adil

机构信息

Paediatric Department, MP Shah Hospital, Nairobi, Kenya.

Paediatric Department, Agakhan University Hospital, Nairobi, Kenya.

出版信息

Pan Afr Med J. 2018 Oct 31;31:153. doi: 10.11604/pamj.2018.31.153.15568. eCollection 2018.

Abstract

Childhood interstitial lung disease (ChILD) is a rare disease and sensitization is needed in the recognition, diagnosis and treatment approaches. There is no formal approach to diagnosis or therapy in resource limited regions. We present a case of a 4-month infant who presented with all the criteria for diagnosis of ChILD. Lung biopsy being the gold standard is a challenge in our setting and diagnosis was based on clinical signs and imaging after ruling out of other similar respiratory conditions by way of individual trials of therapy. Monotherapy with prednisone showed clinical improvement within days of initiation.

摘要

儿童间质性肺疾病(ChILD)是一种罕见疾病,在其识别、诊断和治疗方法上需要敏锐的洞察力。在资源有限的地区,尚无正式的诊断或治疗方法。我们报告一例4个月大的婴儿,其具备ChILD的所有诊断标准。在我们的环境中,肺活检作为金标准是一项挑战,诊断基于临床体征和影像学检查,通过个体化治疗试验排除其他类似的呼吸道疾病后做出。单独使用泼尼松治疗在开始治疗后的几天内就显示出临床改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e19d/6488281/3c393a96434d/PAMJ-31-153-g001.jpg

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