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凝血检测中假性结果的来源与解决方案。

Sources and solutions for spurious test results in coagulation.

机构信息

Department of Pathology, University of New Mexico Health Sciences Center, Albuquerque, New Mexico.

出版信息

Int J Lab Hematol. 2019 May;41 Suppl 1:162-169. doi: 10.1111/ijlh.12989.

DOI:10.1111/ijlh.12989
PMID:31069971
Abstract

In the coagulation laboratory, much emphasis has been placed on rapid and accurate testing; however, spurious results that are inaccurate and do not reflect the actual status of the patient can potentially lead to an incorrect diagnosis and altered intervention. Errors in coagulation results and interpretation can occur at any point of the process from obtaining the specimen to interpretation and use of the result by the clinician. The main sources of error include the patient's biological and preanalytical variation, analytical testing, and postanalytical use of the reported result(s). This article reviews various sources of error leading to spurious results, providing methods to recognize these aberrant results and presenting solutions for minimizing their occurrence.

摘要

在凝血实验室,人们非常重视快速准确的检测;然而,不准确且不能反映患者实际情况的虚假结果可能导致错误的诊断和干预措施的改变。从采集标本到临床医生解释和使用结果的过程中的任何一个环节都可能导致凝血结果和解释的错误。误差的主要来源包括患者的生物学和分析前变异、分析测试以及报告结果的分析后使用。本文回顾了导致虚假结果的各种误差源,提供了识别这些异常结果的方法,并提出了减少其发生的解决方案。

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