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间质性角膜炎的诊断与治疗

Interstitial keratitis diagnosis and treatment.

作者信息

Gauthier A-S, Noureddine S, Delbosc B

机构信息

Service d'ophtalmologie, CHU Jean-Minjoz, 2, boulevard Fleming, 25030 Besançon cedex, France.

Service d'ophtalmologie, CHU Jean-Minjoz, 2, boulevard Fleming, 25030 Besançon cedex, France.

出版信息

J Fr Ophtalmol. 2019 Jun;42(6):e229-e237. doi: 10.1016/j.jfo.2019.04.001. Epub 2019 May 15.

Abstract

Interstitial keratitis is a non-ulcerative, non-suppurative, more or less vascularized inflammation of the corneal stroma. The corneal lesions result from the host response to bacterial, viral (40% of cases) or parasitic antigens, or from an autoimmune response (1% of cases) without active corneal infection. The natural history of the disease is divided into two phases: acute and cicatricial. This type of keratitis is less common than ulcerative bacterial keratitis, but it is a non-negligible cause of visual loss. It is associated with systemic or infectious disease and requires early diagnosis and appropriate treatment to optimize visual prognosis and avoid other complications.

摘要

间质性角膜炎是一种角膜基质的非溃疡性、非化脓性、或多或少伴有血管化的炎症。角膜病变是由宿主对细菌、病毒(40%的病例)或寄生虫抗原的反应引起的,或者是由无活动性角膜感染的自身免疫反应(1%的病例)引起的。该病的自然病程分为两个阶段:急性期和瘢痕期。这种类型的角膜炎比溃疡性细菌性角膜炎少见,但却是导致视力丧失的不可忽视的原因。它与全身性或感染性疾病相关,需要早期诊断和适当治疗,以优化视力预后并避免其他并发症。

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