Department of Women and Children's Health, School of Life Course Sciences, Faculty of Life Sciences and Medicine, King's College London, London, UK.
Neonatal Unit, Evelina London Children's Hospital, Guy's and St Thomas' NHS Foundation Trust, London, UK.
J Perinat Med. 2019 Aug 27;47(6):665-670. doi: 10.1515/jpm-2018-0389.
Background Airway obstruction can occur during facemask (FM) resuscitation of preterm infants at birth. Intubation bypasses any upper airway obstruction. Thus, it would be expected that the occurrence of low expiratory tidal volumes (VTes) would be less in infants resuscitated via an endotracheal tube (ETT) rather than via an FM. Our aim was to test this hypothesis. Methods Analysis was undertaken of respiratory function monitoring traces made during initial resuscitation in the delivery suite to determine the peak inflating pressure (PIP), positive end expiratory pressure (PEEP), the VTe and maximum exhaled carbon dioxide (ETCO2) levels and the number of inflations with a low VTe (less than 2.2 mL/kg). Results Eighteen infants were resuscitated via an ETT and 11 via an FM, all born at less than 29 weeks of gestation. Similar inflation pressures were used in both groups (17.2 vs. 18.8 cmH2O, P = 0.67). The proportion of infants with a low median VTe (P = 0.6) and the proportion of inflations with a low VTe were similar in the groups (P = 0.10), as was the lung compliance (P = 0.67). Infants with the lowest VTe had the stiffest lungs (P < 0.001). Conclusion Respiratory function monitoring during initial resuscitation can objectively identify infants who may require escalation of inflation pressures.
在对早产儿进行面罩(FM)复苏时,气道阻塞可能会发生。插管可绕过任何上呼吸道阻塞。因此,预计通过气管内管(ETT)而不是通过 FM 进行复苏的婴儿发生低呼气潮气量(VTes)的情况会更少。我们的目的是检验这一假设。
对分娩室初始复苏期间进行的呼吸功能监测轨迹进行分析,以确定峰压(PIP)、呼气末正压(PEEP)、VTes 和最大呼出二氧化碳(ETCO2)水平以及低 VTes(小于 2.2 毫升/公斤)的充气次数。
18 名婴儿通过 ETT 复苏,11 名婴儿通过 FM 复苏,均出生于 29 周以下。两组的充气压力相似(17.2 对 18.8 cmH2O,P = 0.67)。低 VTe 的婴儿比例(P = 0.6)和低 VTe 的充气比例在两组中相似(P = 0.10),肺顺应性也相似(P = 0.67)。VTes 最低的婴儿的肺最硬(P < 0.001)。
初始复苏期间的呼吸功能监测可以客观地识别可能需要增加充气压力的婴儿。