Sleep Medicine Department, Sydney Children's Hospital, Randwick, New South Wales, Australia.
School of Women's & Children's Health, Faculty of Medicine, University of New South Wales, Sydney, Australia.
Sleep Breath. 2020 Jun;24(2):703-707. doi: 10.1007/s11325-019-01861-z. Epub 2019 May 19.
Polysomnography (PSG) is the gold standard in the diagnosis of obstructive sleep apnea (OSA). However, due to high cost and limited availability, this is difficult to access and often delayed. To evaluate the reliability of overnight oximetry as a screening tool for OSA diagnosis.
All children suspected of OSA who underwent an overnight oximetry and subsequent PSG between January 2014 and April 2016 were studied retrospectively. The "McGill oximetry scoring" was compared with OSA diagnosis as per the American Association of Sleep Medicine.
A total of 110 patients had both oximetry and PSG. Sixty-one children (56%) had normal oximetry, whereas 30 (27%) had McGill grade 2 and 19 (17%) had McGill 3 and 4. Sixty-four percent (64%) of children with normal oximetry had a normal PSG. Seventy percent (70%) of children with McGill 2 had either a normal or mild OSA on PSG. All the children with McGill 3 and 4 had moderate/severe OSA by PSG. The overall sensitivity and specificity of oximetry in identifying OSA were 63% and 78%, respectively, and the positive and negative predictive values (PPV and NPV) were 78% and 64%, respectively. The sensitivity and specificity of McGill 3 and 4 in diagnosing moderate/severe OSA on PSG were 59% and 100%, respectively, and the PPV and NPV were 100% and 78%, respectively.
Overnight oximetry provides satisfactory diagnostic performance in detecting moderate and severe OSA; however, a normal or McGill 2 score does not rule out OSA and a PSG is required for diagnosis.
多导睡眠图(PSG)是诊断阻塞性睡眠呼吸暂停(OSA)的金标准。然而,由于成本高和可用性有限,这很难获得,并且经常被延迟。评估夜间血氧仪作为 OSA 诊断的筛查工具的可靠性。
回顾性研究了 2014 年 1 月至 2016 年 4 月期间接受过夜血氧仪和随后 PSG 的所有疑似 OSA 儿童。根据美国睡眠医学协会,将“麦吉尔血氧仪评分”与 OSA 诊断进行比较。
共有 110 例患者进行了血氧仪和 PSG 检查。61 名儿童(56%)的血氧仪正常,而 30 名(27%)的儿童麦吉尔评分 2 分,19 名(17%)的儿童麦吉尔评分 3 分和 4 分。64%(64%)的血氧仪正常的儿童 PSG 正常。70%(70%)麦吉尔评分 2 的儿童 PSG 有正常或轻度 OSA。所有麦吉尔评分 3 和 4 的儿童 PSG 均有中重度 OSA。血氧仪识别 OSA 的总体敏感性和特异性分别为 63%和 78%,阳性和阴性预测值(PPV 和 NPV)分别为 78%和 64%。麦吉尔评分 3 和 4 对 PSG 诊断中重度 OSA 的敏感性和特异性分别为 59%和 100%,PPV 和 NPV 分别为 100%和 78%。
夜间血氧仪在检测中重度 OSA 方面具有令人满意的诊断性能;然而,正常或麦吉尔 2 评分不能排除 OSA,需要进行 PSG 诊断。