[非良性快速心律失常新生儿的心率变异性]
[Heart rate variability in neonates with non-benign tachyarrhythmia].
作者信息
Yan Xiao-Tian, Bo Tao, Wang Cheng, Li Fang, Bai Lu
机构信息
Division of Cardiology, Children's Medical Center, Second Xiangya Hospital, Central South University, Changsha 410011, China.
出版信息
Zhongguo Dang Dai Er Ke Za Zhi. 2019 May;21(5):474-478. doi: 10.7499/j.issn.1008-8830.2019.05.015.
OBJECTIVE
To study heart rate variability (HRV) in neonates with non-benign tachyarrhythmia (NNTA) and the role of automatic nervous system (ANS) in NNTA.
METHODS
The neonates who were admitted to the Department of Neonatology, the Second Xiangya Hospital of Central South University, from January 2010 to June 2018 and were diagnosed with NNTA were enrolled as the NNTA group, and the neonates with sinus rhythm or accidental premature beats on ambulatory electrocardiography were enrolled as the control group. Each group was further subdivided into preterm and term subgroups. A retrospective analysis was performed for their clinical data.
RESULTS
A total of 27 NNTA neonates were enrolled, accounting for 0.28% (27/9 632) of all neonates hospitalized during the same period of time, and 53 neonates were enrolled in the control group. Compared with the preterm and term control subgroups, the preterm NNTA and term NNTA subgroups had a significant increase in the standard deviation of average RR interval (P<0.05).
CONCLUSIONS
Immature and unbalanced ANS function may play an important role in the development and progression of NNTA.
目的
研究非良性快速心律失常（NNTA）新生儿的心率变异性（HRV）以及自主神经系统（ANS）在NNTA中的作用。
方法
选取2010年1月至2018年6月在中南大学湘雅二医院新生儿科住院且诊断为NNTA的新生儿作为NNTA组，选取动态心电图显示为窦性心律或偶发早搏的新生儿作为对照组。每组再进一步分为早产和足月亚组。对其临床资料进行回顾性分析。
结果
共纳入27例NNTA新生儿，占同期住院新生儿总数的0.28%（27/9 632），对照组纳入53例新生儿。与早产和足月对照组亚组相比，早产NNTA亚组和足月NNTA亚组的平均RR间期标准差显著增加（P<0.05）。
结论
不成熟且失衡的ANS功能可能在NNTA的发生和发展中起重要作用。
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