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医生在治疗动脉粥样硬化性心血管疾病患者时对血液胆固醇治疗指南的遵循情况。

Adherence to Blood Cholesterol Treatment Guidelines Among Physicians Managing Patients With Atherosclerotic Cardiovascular Disease.

机构信息

Reliant Medical Group, Worcester, Massachusetts.

Amgen Inc., Thousand Oaks, California.

出版信息

Am J Cardiol. 2019 Jul 15;124(2):169-175. doi: 10.1016/j.amjcard.2019.04.017. Epub 2019 Apr 23.

Abstract

The ACC/AHA blood cholesterol treatment guidelines recommend statin therapy for all patients after experiencing an acute cardiovascular event. Previous analyses have shown that physicians have been slow to adopt guidelines, and many patients remain untreated or undertreated with statins after a cardiovascular event. However, reasons for this remain unknown. This analysis used electronic medical records and patient chart data from Reliant Medical Group (Worcester, Massachusetts) to evaluate physician adherence to the 2013 ACC/AHA blood cholesterol guidelines when treating patients with evidence of acute atherosclerotic cardiovascular disease and the reasons for the observed treatment decisions. Less than 50% of acute atherosclerotic cardiovascular disease patients were treated according to the ACC/AHA guidelines. Nearly 42% of patients not treated according to guidelines received a lower statin intensity than recommended. The most common reason cited by 41.8% of physicians for treating with a statin intensity below the recommended intensity was low-density lipoprotein cholesterol stable or at goal, despite ACC/AHA guidelines recommending specific statin intensities rather than specific low-density lipoprotein cholesterol levels. In conclusion, physician and patient education on the importance of maximizing lipid-lowering therapy in this high-risk patient population should be emphasized.

摘要

美国心脏病学会/美国心脏协会的血胆固醇治疗指南建议所有经历急性心血管事件的患者进行他汀类药物治疗。先前的分析表明,医生在采用指南方面一直进展缓慢,许多患者在发生心血管事件后仍未接受他汀类药物治疗或接受的他汀类药物治疗不足。然而,其原因尚不清楚。本分析使用了来自 Reliant Medical Group(马萨诸塞州伍斯特)的电子病历和患者图表数据,以评估医生在治疗有急性动脉粥样硬化性心血管疾病证据的患者时对 2013 年 ACC/AHA 血胆固醇指南的依从性,以及观察到的治疗决策的原因。不到 50%的急性动脉粥样硬化性心血管疾病患者按照 ACC/AHA 指南进行治疗。近 42%的未按指南治疗的患者接受的他汀类药物强度低于推荐强度。41.8%的医生表示,尽管 ACC/AHA 指南建议特定的他汀类药物强度而不是特定的低密度脂蛋白胆固醇水平,但治疗强度低于推荐强度的最常见原因是低密度脂蛋白胆固醇稳定或达标。总之,应该强调对这一高危患者人群进行最大程度降低血脂治疗的重要性,以对医生和患者进行教育。

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