Altamimi Eyad M, Alorjani Mohammed S, Alquran Wejdan Y
Department of Pediatrics, Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan.
Department of Pathology, Faculty of Medicine, Jordan University of science and Technology, Irbid, Jordan.
Pediatr Gastroenterol Hepatol Nutr. 2019 May;22(3):298-302. doi: 10.5223/pghn.2019.22.3.298. Epub 2019 Apr 17.
A previously healthy 2.5-year-old male child presented with vomiting, diarrhea, and fever. During hospitalization he developed odynophagia and refusal to eat. His symptoms did not respond to acid suppressant therapy. He underwent upper endoscopy which showed severe inflammation, ulcerations and abundant necrosis. Histopathological features and serological testing were consistent with herpetic esophagitis. He had no history of recurrent infections or history of sick contacts. His immunological work up showed normal level of immunoglobulins and his White Blood Cells subpopulations were normal. His HSV serology was positive. The patient was started on acyclovir 5 mg/kg q 8 hours. He resolved his symptoms within 24 hours of treatment.
一名既往健康的2.5岁男童出现呕吐、腹泻和发热症状。住院期间,他出现吞咽疼痛并拒绝进食。其症状对抑酸治疗无反应。他接受了上消化道内镜检查,结果显示有严重炎症、溃疡和大量坏死。组织病理学特征和血清学检测结果与疱疹性食管炎相符。他没有反复感染史或接触过患病者的病史。他的免疫功能检查显示免疫球蛋白水平正常,白细胞亚群也正常。他的单纯疱疹病毒血清学检测呈阳性。该患者开始接受阿昔洛韦治疗,剂量为5毫克/千克,每8小时一次。治疗24小时内他的症状得到缓解。