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巴西牛分枝杆菌克隆复合体的鉴定。

Identification of clonal complexes of Mycobacterium bovis in Brazil.

机构信息

Laboratório Nacional Agropecuário de Minas Gerais, Pedro Leopoldo, Minas Gerais, Brazil.

Laboratório Nacional Agropecuário de Pernambuco, Recife, Pernambuco, Brazil.

出版信息

Arch Microbiol. 2019 Oct;201(8):1047-1051. doi: 10.1007/s00203-019-01674-4. Epub 2019 May 20.

Abstract

Bovine tuberculosis is a disease that is widely distributed around the world. Its causative agent, Mycobacterium bovis, has characteristics of a microorganism with clonal multiplication in populations with no evidence of genetic exchange between strains, and, consequently, a group of strains can be identified as descending from a common ancestor. The aim of this study was to investigate the clonal complexes of M. bovis isolated from samples of lesions suggestive of bovine tuberculosis collected from slaughterhouses in various states of Brazil between 2006 and 2012. Ninety samples were analyzed, and it was found that 14.4% belonged to the clonal complex European1 and 81.1% to the clonal complex European2, while 4.65% were not identified as any of the four known complexes.

摘要

牛结核病是一种广泛分布于世界各地的疾病。其病原体牛分枝杆菌具有微生物的特征,在种群中呈克隆性繁殖,没有菌株间遗传交换的证据,因此可以鉴定出一组菌株是从一个共同祖先衍生而来的。本研究旨在调查 2006 年至 2012 年间从巴西各地屠宰场疑似牛结核病病变样本中分离出的牛分枝杆菌的克隆复合体。对 90 个样本进行了分析,发现 14.4%属于克隆复合体欧洲 1,81.1%属于克隆复合体欧洲 2,而 4.65%不属于已知的四个复合体之一。

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