[舌下神经刺激治疗阻塞性睡眠呼吸暂停；技术、适应症及未来前景]
[Hypoglossal nerve stimulation for obstructive sleep apnoea; technique, indication and future prospects].
作者信息
Vonk Patty E, Benoist Linda B L, Kasius Kristel M, van Maanen J Peter, Ravesloot Madeline J L, Reesink Herre J, de Vries Nico
机构信息
OLVG, afd. Keel-, Neus- en Oorheelkunde/Hoofd-Halschirurgie, Amsterdam.
Contact: P.E. Vonk (
出版信息
Ned Tijdschr Geneeskd. 2019 May 3;163:D3286.
Hypoglossal nerve stimulation for obstructive sleep apnoea; technique, indication and future prospects Continuous positive airway pressure (CPAP) is the treatment of first choice in patients with moderate to severe obstructive sleep apnoea (OSA); however, 1 in 3 patients does not tolerate CPAP. Upper airway stimulation (UAS) is an alternative for CPAP. This is a new treatment, intended for patients with CPAP intolerance or failure. The muscles responsible for protrusion of the tongue are activated by unilateral stimulation of the hypoglossal nerve, resulting in opening up of the pharynx. Since April 2017, UAS treatment has been reimbursed for a select group of patients by the National Healthcare Institute in the Netherlands, leading to an increase in demand for UAS.
舌下神经刺激治疗阻塞性睡眠呼吸暂停；技术、适应证及未来前景 持续气道正压通气（CPAP）是中重度阻塞性睡眠呼吸暂停（OSA）患者的首选治疗方法；然而，三分之一的患者不耐受CPAP。上气道刺激（UAS）是CPAP的替代方法。这是一种新的治疗方法，适用于CPAP不耐受或治疗失败的患者。通过单侧刺激舌下神经来激活负责舌头前伸的肌肉，从而使咽部张开。自2017年4月以来，荷兰国家卫生保健研究所已为部分特定患者报销UAS治疗费用，这导致对UAS的需求增加。
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