Department of Ophthalmology and Visual Sciences, Paulista School of Medicine, Federal University of São Paulo, UNIFESP, Sao Paulo, Brazil.
Ocul Immunol Inflamm. 2020 Apr 2;28(3):402-408. doi: 10.1080/09273948.2019.1588982. Epub 2019 May 23.
To evaluate the characteristics of Vogt-Koyanagi-Harada (VKH) syndrome in Brazilian children.M Clinical data were obtained from the medical records of six children with VKH disease from March 2014 to June 2018 at the Federal University of São Paulo, Brazil. Six patients met the diagnostic criteria for VKH. The patients, who ranged in age from 5 to 8 years, all presented with chronic disease. The most common ocular finding was abnormal fundus pigmentation in five patients followed by band keratopathy in four. Two patients had glaucoma, cataract, and subretinal neovascularization. The final visual acuity was less than 20/40 in 50% of the eyes. Visual outcomes were favorable in half of patients depending on the long-term sequelae. VKH is rarely reported in children and it may be sight-threatening, and requires careful attention, being an important differential diagnosis.
评估巴西儿童 Vogt-Koyanagi-Harada(VKH)综合征的特征。方法临床资料来源于 2014 年 3 月至 2018 年 6 月巴西圣保罗联邦大学 6 例 VKH 疾病儿童的病历。6 例患者符合 VKH 的诊断标准。年龄 5 至 8 岁的患者均为慢性疾病。最常见的眼部表现为 5 例眼底色素异常,4 例带状角膜病变。2 例患者有青光眼、白内障和视网膜下新生血管。50%的眼最终视力低于 20/40。根据长期后遗症,一半的患者的视力预后良好。VKH 在儿童中罕见,可能威胁视力,需要仔细关注,是一个重要的鉴别诊断。