Department of Renal Medicine, King's College Hospital, London, UK
Department of Renal Medicine, King's College Hospital, London, UK.
Perit Dial Int. 2019 Jul-Aug;39(4):350-355. doi: 10.3747/pdi.2017.00214. Epub 2019 May 23.
Exit-site infection (ESI) and tunnel infection (TI) of the peritoneal dialysis (PD) catheter are significant causes of catheter or even method loss as well as patient morbidity. Among the methods that have been in use thus far, the removal and replacement of the catheter often needs to be followed by switching temporarily to hemodialysis, whereas catheter splicing or unroofing of the tunnel tract and shaving/removal of the superficial catheter cuff have not gained universal acceptance thus far.We treat chronic ESI with exit-site relocation under local anesthetic with removal of the external cuff. For the purposes of this study, we conducted a retrospective cohort analysis of all exit-site relocations performed using that technique over a 5-year period.Twenty-seven patients (16 male, mean age 58 years, range 23 - 81 years) with chronic ESI underwent exit-site relocation under local anesthetic as a day-case procedure. Follow-up was 47.5 ± 22.4 months (range 10.8 - 79.4 months). No dialysate leaks occurred following the procedure. Peritoneal dialysis was resumed immediately. The procedure resulted in long-term resolution of the infection in 20 of the 27 patients (74%). In 7 patients (26%), the catheter had to be removed eventually, either because of ESI recurrence (5 patients) or TI (2 patients), which in 2 cases was subsequently complicated by PD peritonitis, and the patients were switched to hemodialysis.The technique described herein is a safe, straightforward, and effective method for the treatment of chronic ESI while the patient remains on PD and avoids switching to hemodialysis.
出口部位感染(ESI)和隧道感染(TI)是腹膜透析(PD)导管的重要原因,可导致导管甚至治疗方法丢失以及患者发病率升高。迄今为止,在已使用的方法中,导管的移除和更换通常需要暂时切换到血液透析,而导管拼接或隧道切开术和浅层导管袖套刮除/切除尚未得到普遍接受。我们在局部麻醉下使用出口部位重新定位来治疗慢性 ESI,并去除外部袖套。在这项研究中,我们对使用该技术在 5 年内进行的所有出口部位重新定位进行了回顾性队列分析。27 例慢性 ESI 患者(男 16 例,平均年龄 58 岁,范围 23-81 岁)在局部麻醉下作为日间手术进行出口部位重新定位。随访时间为 47.5±22.4 个月(范围 10.8-79.4 个月)。术后无透析液泄漏。腹膜透析立即恢复。该手术导致 27 例患者中的 20 例(74%)的感染长期得到解决。在 7 例患者(26%)中,最终不得不移除导管,要么是因为 ESI 复发(5 例),要么是因为 TI(2 例),其中 2 例随后并发 PD 腹膜炎,患者转为血液透析。在患者继续接受 PD 治疗的同时,该方法是一种安全、直接且有效的治疗慢性 ESI 的方法,可避免切换到血液透析。