Neurology and Division of Headache Medicine, Stanford University, Stanford, CA, USA.
Curr Pain Headache Rep. 2019 May 23;23(6):44. doi: 10.1007/s11916-019-0785-x.
Subarachnoid hemorrhage is a serious and life-threatening medical condition which commonly presents with an acute headache. Unfortunately, it remains frequently misdiagnosed at initial presentation with dire consequences in terms of patient morbidity and mortality. The goal of this paper is to review salient features in the clinical history, as well as recently developed clinical decision rules, which can help determine which patients warrant further investigation for subarachnoid hemorrhage when the initial presentation is that of an acute headache.
A recent prospective observational study showed that occipital location, stabbing quality, presence of meningism, and onset of headache during exertion were characteristics in the clinical history that can distinguish the headache of SAH from other causes. The Ottawa headache rule is a clinical decision tool which was developed to help identify patients presenting to the ED with acute non-traumatic headache who require investigation to rule out subarachnoid hemorrhage. Using this tool, it is recommended that patients who meet any one of the following 6 criteria are investigated further: Onset greater than or equal to 40 years, presence of neck pain or stiffness, witnessed loss of consciousness, onset during exertion, thunder clap headache (pain peaking within 1 s), or limited neck flexion on exam. An informed and thoughtful approach that takes into account the timing, presentation, risk factors, and resources, as discussed here, should help distinguish between the patient that warrants further evaluation and intervention for SAH and one who does not. The Ottawa SAH rule is a useful clinical decision tool for young inexperienced clinicians in order to avoid missed diagnoses. However, its clinical value is limited by its low specificity. Clinical decision tools with higher specificity are needed.
蛛网膜下腔出血是一种严重且危及生命的疾病,通常表现为急性头痛。然而,它在初始表现时经常被误诊,这给患者的发病率和死亡率带来了严重后果。本文的目的是回顾病史中的显著特征,以及最近开发的临床决策规则,这些规则可以帮助确定哪些患者在初始表现为急性头痛时需要进一步调查蛛网膜下腔出血。
最近一项前瞻性观察研究表明,头痛的位置(枕部)、性质(刺痛)、脑膜刺激征的存在,以及活动时头痛发作是蛛网膜下腔出血头痛与其他原因头痛相鉴别的特征。渥太华头痛规则是一种临床决策工具,用于帮助确定因急性非创伤性头痛就诊于急诊科的患者是否需要进一步检查以排除蛛网膜下腔出血。使用该工具,建议符合以下 6 项标准之一的患者进行进一步检查:年龄≥40 岁、颈痛或僵硬、目击者意识丧失、活动时发作、霹雳样头痛(疼痛在 1 秒内达到峰值)或体检时颈部活动受限。正如这里所讨论的,考虑到时机、表现、风险因素和资源,采取明智和深思熟虑的方法,应该有助于区分需要进一步评估和干预蛛网膜下腔出血的患者和不需要的患者。渥太华蛛网膜下腔出血规则是一种用于经验不足的年轻临床医生的有用的临床决策工具,以避免漏诊。然而,其临床价值受到低特异性的限制,需要特异性更高的临床决策工具。