Biocruces Bizkaia Health Research Institute, Cruces University Hospital, Barakaldo, 48903, Spain.
Neuropsychology Service, Alberta Children's Hospital, Calgary, Alberta, T3B 6A8, Canada.
J Int Neuropsychol Soc. 2019 Sep;25(8):834-844. doi: 10.1017/S135561771900050X. Epub 2019 May 27.
To determine the prevalence of low scores for two neuropsychological tests with five total scores that evaluate learning and memory functions.
N = 5402 healthy adults from 11 countries in Latin America and the commonwealth of Puerto Rico were administered the Rey-Osterrieth Complex Figure (ROCF) and the Hopkins Verbal Learning Test (HVLT-R). Two-thirds of the participants were women, and the average age was 53.5 ± 20.0 years. Z-scores were calculated for ROCF Copy and Memory scores and HVLT-R Total Recall, Delayed Recall, and Recognition scores, adjusting for age, age2, sex, education, and interaction variables if significant for the given country. Each Z-score was converted to a percentile for each of the five subtest scores. Each participant was categorized based on his/her number of low scoring tests in specific percentile cutoff groups (25th, 16th, 10th, 5th, and 2nd).
Between 57.3% (El Salvador) and 64.6% (Bolivia) of the sample scored below the 25th percentile on at least one of the five scores. Between 27.1% (El Salvador) and 33.9% (Puerto Rico) scored below the 10th percentile on at least one of the five subtests. Between 5.9% (Chile, El Salvador, Peru) and 10.3% (Argentina) scored below the 2nd percentile on at least one of the five scores.
Results are consistent with other studies that found that low scores are common when multiple neuropsychological outcomes are evaluated in healthy individuals. Clinicians should consider the higher probability of low scores when evaluating learning and memory using various sets of scores to reduce false-positive diagnoses of cognitive deficits.
确定 5 项总分评估学习和记忆功能的神经心理学测试中,两个测试的低分数发生率。
来自拉丁美洲 11 个国家和波多黎各的 5402 名健康成年人接受了 Rey-Osterrieth 复杂图形测试(ROCF)和 Hopkins 语言学习测试(HVLT-R)。三分之二的参与者为女性,平均年龄为 53.5±20.0 岁。ROCF 复制和记忆分数以及 HVLT-R 总回忆、延迟回忆和识别分数的 Z 分数是根据年龄、年龄平方、性别、教育程度以及显著的交互变量进行计算的。每个 Z 分数都转换为五个子测试分数的百分位数。根据每个参与者在特定百分位截断组(第 25、16、10、5 和 2 位)中的低分数测试数量对其进行分类。
在样本中,至少有一个测试的五个分数中有 57.3%(萨尔瓦多)到 64.6%(玻利维亚)的人低于第 25 百分位。在五个子测试中,至少有一个测试的 27.1%(萨尔瓦多)到 33.9%(波多黎各)的人低于第 10 百分位。在至少一个测试中,有 5.9%(智利、萨尔瓦多、秘鲁)到 10.3%(阿根廷)的人低于第 2 百分位。
这些结果与其他研究一致,即当评估健康个体的多项神经心理学结果时,低分数是常见的。当使用各种分数集评估学习和记忆时,临床医生应考虑到低分数的可能性更高,以减少认知缺陷的误诊。