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成人脊柱畸形矫正术后与年龄调整后对线目标的偏差及相关代偿性募集的全身X线分析

Full-Body Radiographic Analysis of Postoperative Deviations From Age-Adjusted Alignment Goals in Adult Spinal Deformity Correction and Related Compensatory Recruitment.

作者信息

Passias Peter G, Jalai Cyrus M, Diebo Bassel G, Cruz Dana L, Poorman Gregory W, Buckland Aaron J, Day Louis M, Horn Samantha R, Liabaud Barthélemy, Lafage Renaud, Soroceanu Alexandra, Baker Joseph F, McClelland Shearwood, Oren Jonathan H, Errico Thomas J, Schwab Frank J, Lafage Virginie

机构信息

Department of Orthopaedic Surgery, Hospital for Joint Diseases, NYU Langone Medical Center, New York, New York.

Department of Orthopaedic Surgery, Hospital for Special Surgery, New York, New York.

出版信息

Int J Spine Surg. 2019 Apr 30;13(2):205-214. doi: 10.14444/6028. eCollection 2019 Apr.

Abstract

BACKGROUND

Full-body stereographs for adult spinal deformity (ASD) have enhanced global deformity and lower-limb compensation associations. The advent of age-adjusted goals for classic ASD parameters (sagittal vertical axis, pelvic tilt, spino-pelvic mismatch [PI-LL]) has enabled individualized evaluation of successful versus failed realignment, though these remain to be radiographically assessed postoperatively. This study analyzes pre- and postoperative sagittal alignment to quantify patient-specific correction against age-adjusted goals, and presents differences in compensation in patients whose postoperative profile deviates from targets.

METHODS

Single-center retrospective review of ASD patients ≥ 18 years with biplanar full-body stereographic x-rays. Inclusion: ≥ 4 levels fused, complete baseline and early (≤ 6-month) follow-up imaging. Correction groups generated at postoperative visit for actual alignment compared to age-adjusted ideal values for pelvic tilt, PI-LL, and sagittal vertical axis derived from clinically relevant formulas. Patients that matched exact ± 10-year threshold for age-adjusted targets were compared to unmatched cases (undercorrected or overcorrected). Comparison of spinal alignment and compensatory mechanisms (thoracic kyphosis, hip extension, knee flexion, ankle flexion, pelvic shift) across correction groups were performed with ANOVA and paired tests.

RESULTS

The sagittal vertical axis, pelvic tilt, and PI-LL of 122 patients improved at early postoperative visits ( < .001). Of lower-extremity parameters, knee flexion and pelvic shift improved ( < .001), but hip extension and ankle flexion were similar ( > .170); global sagittal angle decreased overall, reflecting global postoperative correction (8.3° versus 4.4°,  < .001). Rates of undercorrection to age-adjusted targets for each spino-pelvic parameter were 30.3% (sagittal vertical axis), 41.0% (pelvic tilt), and 43.6% (PI-LL). Compared to matched/overcorrections, undercorrections recruited increased posterior pelvic shift to compensate ( < .001); knee flexion was recruited in undercorrections for sagittal vertical axis and pelvic tilt; thoracic hypokyphosis was observed in PI-LL undercorrections. All undercorrected groups displayed consequentially larger global sagittal angle ( < .001).

CONCLUSIONS

Global alignment cohort improvements were observed, and when comparing actual to age-adjusted alignment, undercorrections recruited pelvic and lower-limb flexion to compensate.

LEVEL OF EVIDENCE

摘要

背景

用于成人脊柱畸形(ASD)的全身立体照片增强了整体畸形与下肢代偿之间的关联。经典ASD参数(矢状垂直轴、骨盆倾斜、脊柱-骨盆失配[PI-LL])年龄调整目标的出现,使得能够对成功与失败的复位进行个体化评估,尽管这些仍需在术后进行影像学评估。本研究分析术前和术后矢状面排列,以根据年龄调整目标量化患者特异性矫正,并呈现术后轮廓偏离目标的患者在代偿方面的差异。

方法

对年龄≥18岁的ASD患者进行单中心回顾性研究,患者均有双平面全身立体X线片。纳入标准:融合节段≥4个,有完整的基线和早期(≤6个月)随访影像学资料。在术后随访时,根据临床相关公式得出的骨盆倾斜、PI-LL和矢状垂直轴的年龄调整理想值,生成实际排列的矫正组。将年龄调整目标精确匹配±10年阈值的患者与不匹配的病例(矫正不足或过度矫正)进行比较。采用方差分析和配对检验比较各矫正组的脊柱排列和代偿机制(胸椎后凸、髋关节伸展、膝关节屈曲、踝关节屈曲、骨盆移位)。

结果

122例患者的矢状垂直轴、骨盆倾斜和PI-LL在术后早期随访时有所改善(P<0.001)。在下肢参数中,膝关节屈曲和骨盆移位有所改善(P<0.001),但髋关节伸展和踝关节屈曲相似(P>0.170);整体矢状角总体下降,反映了术后整体矫正(8.3°对4.4°,P<0.001)。每个脊柱-骨盆参数矫正不足达到年龄调整目标的比例分别为30.3%(矢状垂直轴)、41.0%(骨盆倾斜)和43.6%(PI-LL)。与匹配/过度矫正相比,矫正不足的患者增加了骨盆后移以进行代偿(P<0.001);矢状垂直轴和骨盆倾斜矫正不足时会增加膝关节屈曲;PI-LL矫正不足时观察到胸椎后凸减小。所有矫正不足的组整体矢状角均显著增大(P<0.001)。

结论

观察到整体排列队列有所改善,在将实际排列与年龄调整排列进行比较时,矫正不足的患者会利用骨盆和下肢屈曲进行代偿。

证据水平

3级。

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